Nash NR - Search Results

1

Functional screening of drug target genes: m1 muscarinic acetylcholine receptor phenotypes in degenerative dementias.

Weiner DM, Goodman MW, Colpitts TM, Feddock MA, Duggento KL, Nash NR, Levey AI, Brann MR. Weiner DM, et al. Among authors: nash nr. Am J Pharmacogenomics. 2004;4(2):119-28. doi: 10.2165/00129785-200404020-00006. Am J Pharmacogenomics. 2004. PMID: 15059034

2

The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine.

Weiner DM, Meltzer HY, Veinbergs I, Donohue EM, Spalding TA, Smith TT, Mohell N, Harvey SC, Lameh J, Nash N, Vanover KE, Olsson R, Jayathilake K, Lee M, Levey AI, Hacksell U, Burstein ES, Davis RE, Brann MR. Weiner DM, et al. Psychopharmacology (Berl). 2004 Dec;177(1-2):207-16. doi: 10.1007/s00213-004-1940-5. Epub 2004 Jul 16. Psychopharmacology (Berl). 2004. PMID: 15258717

3

Integrative functional assays, chemical genomics and high throughput screening: harnessing signal transduction pathways to a common HTS readout.

Burstein ES, Piu F, Ma JN, Weissman JT, Currier EA, Nash NR, Weiner DM, Spalding TA, Schiffer HH, Del Tredici AL, Brann MR. Burstein ES, et al. Among authors: nash nr. Curr Pharm Des. 2006;12(14):1717-29. doi: 10.2174/138161206776873662. Curr Pharm Des. 2006. PMID: 16712484

4

Molecular cloning and pharmacology of functionally distinct isoforms of the human histamine H(3) receptor.

Wellendorph P, Goodman MW, Burstein ES, Nash NR, Brann MR, Weiner DM. Wellendorph P, et al. Among authors: nash nr. Neuropharmacology. 2002 Jun;42(7):929-40. doi: 10.1016/s0028-3908(02)00041-2. Neuropharmacology. 2002. PMID: 12069903

5

Discovery of novel peptide/receptor interactions: identification of PHM-27 as a potent agonist of the human calcitonin receptor.

Ma JN, Currier EA, Essex A, Feddock M, Spalding TA, Nash NR, Brann MR, Burstein ES. Ma JN, et al. Among authors: nash nr. Biochem Pharmacol. 2004 Apr 1;67(7):1279-84. doi: 10.1016/j.bcp.2003.11.008. Biochem Pharmacol. 2004. PMID: 15013843

6

Chemical genomics: massively parallel technologies for rapid lead identification and target validation.

Hacksell U, Nash N, Burstein ES, Piu F, Croston G, Brann MR. Hacksell U, et al. Cytotechnology. 2002 Jan;38(1-3):3-10. doi: 10.1023/A:1021169023731. Cytotechnology. 2002. PMID: 19003080 Free PMC article.

7

5-hydroxytryptamine2A receptor inverse agonists as antipsychotics.

Weiner DM, Burstein ES, Nash N, Croston GE, Currier EA, Vanover KE, Harvey SC, Donohue E, Hansen HC, Andersson CM, Spalding TA, Gibson DF, Krebs-Thomson K, Powell SB, Geyer MA, Hacksell U, Brann MR. Weiner DM, et al. J Pharmacol Exp Ther. 2001 Oct;299(1):268-76. J Pharmacol Exp Ther. 2001. PMID: 11561089

8

Identification of novel selective V2 receptor non-peptide agonists.

Del Tredici AL, Vanover KE, Knapp AE, Bertozzi SM, Nash NR, Burstein ES, Lameh J, Currier EA, Davis RE, Brann MR, Mohell N, Olsson R, Piu F. Del Tredici AL, et al. Among authors: nash nr. Biochem Pharmacol. 2008 Oct 30;76(9):1134-41. doi: 10.1016/j.bcp.2008.08.004. Epub 2008 Aug 12. Biochem Pharmacol. 2008. PMID: 18761325

9

Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954).

Croston GE, Olsson R, Currier EA, Burstein ES, Weiner D, Nash N, Severance D, Allenmark SG, Thunberg L, Ma JN, Mohell N, O'Dowd B, Brann MR, Hacksell U. Croston GE, et al. J Med Chem. 2002 Nov 7;45(23):4950-3. doi: 10.1021/jm025551+. J Med Chem. 2002. PMID: 12408704

10

Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist.

Burstein ES, Ma J, Wong S, Gao Y, Pham E, Knapp AE, Nash NR, Olsson R, Davis RE, Hacksell U, Weiner DM, Brann MR. Burstein ES, et al. Among authors: nash nr. J Pharmacol Exp Ther. 2005 Dec;315(3):1278-87. doi: 10.1124/jpet.105.092155. Epub 2005 Aug 31. J Pharmacol Exp Ther. 2005. PMID: 16135699

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