Packham G - Search Results

1

Current strategies to target the anti-apoptotic Bcl-2 protein in cancer cells.

Osford SM, Dallman CL, Johnson PW, Ganesan A, Packham G. Osford SM, et al. Among authors: packham g. Curr Med Chem. 2004 Apr;11(8):1031-9. doi: 10.2174/0929867043455486. Curr Med Chem. 2004. PMID: 15083809 Review.

2

Identification of a novel human BCL-X promoter and exon.

MacCarthy-Morrogh L, Wood L, Brimmell M, Johnson PW, Packham G. MacCarthy-Morrogh L, et al. Among authors: packham g. Oncogene. 2000 Nov 16;19(48):5534-8. doi: 10.1038/sj.onc.1203949. Oncogene. 2000. PMID: 11114731

3

BAG-1 expression and function in human cancer.

Cutress RI, Townsend PA, Brimmell M, Bateman AC, Hague A, Packham G. Cutress RI, et al. Among authors: packham g. Br J Cancer. 2002 Oct 7;87(8):834-9. doi: 10.1038/sj.bjc.6600538. Br J Cancer. 2002. PMID: 12373595 Free PMC article. Review.

4

Differential regulation of cell survival by CD40.

Dallman C, Johnson PW, Packham G. Dallman C, et al. Among authors: packham g. Apoptosis. 2003 Jan;8(1):45-53. doi: 10.1023/a:1021696902187. Apoptosis. 2003. PMID: 12510151 Review.

5

The nuclear BAG-1 isoform, BAG-1L, enhances oestrogen-dependent transcription.

Cutress RI, Townsend PA, Sharp A, Maison A, Wood L, Lee R, Brimmell M, Mullee MA, Johnson PW, Royle GT, Bateman AC, Packham G. Cutress RI, et al. Among authors: packham g. Oncogene. 2003 Aug 7;22(32):4973-82. doi: 10.1038/sj.onc.1206688. Oncogene. 2003. PMID: 12902980

6

TEL, a putative tumor suppressor, induces apoptosis and represses transcription of Bcl-XL.

Irvin BJ, Wood LD, Wang L, Fenrick R, Sansam CG, Packham G, Kinch M, Yang E, Hiebert SW. Irvin BJ, et al. Among authors: packham g. J Biol Chem. 2003 Nov 21;278(47):46378-86. doi: 10.1074/jbc.M305189200. Epub 2003 Sep 5. J Biol Chem. 2003. PMID: 12960174 Free article.

7

Total synthesis of spiruchostatin A, a potent histone deacetylase inhibitor.

Yurek-George A, Habens F, Brimmell M, Packham G, Ganesan A. Yurek-George A, et al. Among authors: packham g. J Am Chem Soc. 2004 Feb 4;126(4):1030-1. doi: 10.1021/ja039258q. J Am Chem Soc. 2004. PMID: 14746465

8

Mcl-1 is required for Akata6 B-lymphoma cell survival and is converted to a cell death molecule by efficient caspase-mediated cleavage.

Michels J, O'Neill JW, Dallman CL, Mouzakiti A, Habens F, Brimmell M, Zhang KY, Craig RW, Marcusson EG, Johnson PW, Packham G. Michels J, et al. Among authors: packham g. Oncogene. 2004 Jun 17;23(28):4818-27. doi: 10.1038/sj.onc.1207648. Oncogene. 2004. PMID: 15122313

9

2-MeOE2bisMATE induces caspase-dependent apoptosis in CAL51 breast cancer cells and overcomes resistance to TRAIL via cooperative activation of caspases.

Wood L, Leese MP, Mouzakiti A, Purohit A, Potter BV, Reed MJ, Packham G. Wood L, et al. Among authors: packham g. Apoptosis. 2004 May;9(3):323-32. doi: 10.1023/b:appt.0000025809.80684.bd. Apoptosis. 2004. PMID: 15258464

10

Mcl-1.

Michels J, Johnson PW, Packham G. Michels J, et al. Among authors: packham g. Int J Biochem Cell Biol. 2005 Feb;37(2):267-71. doi: 10.1016/j.biocel.2004.04.007. Int J Biochem Cell Biol. 2005. PMID: 15474972 Review.

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