Baba M - Search Results

1

Novel 4'-substituted stavudine analog with improved anti-human immunodeficiency virus activity and decreased cytotoxicity.

Dutschman GE, Grill SP, Gullen EA, Haraguchi K, Takeda S, Tanaka H, Baba M, Cheng YC. Dutschman GE, et al. Among authors: baba m. Antimicrob Agents Chemother. 2004 May;48(5):1640-6. doi: 10.1128/AAC.48.5.1640-1646.2004. Antimicrob Agents Chemother. 2004. PMID: 15105115 Free PMC article.

2

Anti-human immunodeficiency virus type 1 activity and resistance profile of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine in vitro.

Nitanda T, Wang X, Kumamoto H, Haraguchi K, Tanaka H, Cheng YC, Baba M. Nitanda T, et al. Among authors: baba m. Antimicrob Agents Chemother. 2005 Aug;49(8):3355-60. doi: 10.1128/AAC.49.8.3355-3360.2005. Antimicrob Agents Chemother. 2005. PMID: 16048947 Free PMC article.

3

Highly selective action of triphosphate metabolite of 4'-ethynyl D4T: a novel anti-HIV compound against HIV-1 RT.

Yang G, Dutschman GE, Wang CJ, Tanaka H, Baba M, Anderson KS, Cheng YC. Yang G, et al. Among authors: baba m. Antiviral Res. 2007 Mar;73(3):185-91. doi: 10.1016/j.antiviral.2006.10.002. Epub 2006 Nov 10. Antiviral Res. 2007. PMID: 17109975

4

Comparison of the phosphorylation of 4'-ethynyl 2',3'-dihydro-3'-deoxythymidine with that of other anti-human immunodeficiency virus thymidine analogs.

Hsu CH, Hu R, Dutschman GE, Yang G, Krishnan P, Tanaka H, Baba M, Cheng YC. Hsu CH, et al. Among authors: baba m. Antimicrob Agents Chemother. 2007 May;51(5):1687-93. doi: 10.1128/AAC.01432-06. Epub 2007 Mar 12. Antimicrob Agents Chemother. 2007. PMID: 17353236 Free PMC article.

5

Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog.

Paintsil E, Dutschman GE, Hu R, Grill SP, Lam W, Baba M, Tanaka H, Cheng YC. Paintsil E, et al. Among authors: baba m. Antimicrob Agents Chemother. 2007 Nov;51(11):3870-9. doi: 10.1128/AAC.00692-07. Epub 2007 Aug 27. Antimicrob Agents Chemother. 2007. PMID: 17724147 Free PMC article.

6

Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase by a stavudine analogue, 4'-ethynyl stavudine triphosphate.

Yang G, Wang J, Cheng Y, Dutschman GE, Tanaka H, Baba M, Cheng YC. Yang G, et al. Among authors: baba m. Antimicrob Agents Chemother. 2008 Jun;52(6):2035-42. doi: 10.1128/AAC.00083-08. Epub 2008 Apr 7. Antimicrob Agents Chemother. 2008. PMID: 18391035 Free PMC article.

7

Retention of metabolites of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel anti-human immunodeficiency virus type 1 thymidine analog, in cells.

Wang X, Tanaka H, Baba M, Cheng YC. Wang X, et al. Among authors: baba m. Antimicrob Agents Chemother. 2009 Aug;53(8):3317-24. doi: 10.1128/AAC.00302-09. Epub 2009 May 26. Antimicrob Agents Chemother. 2009. PMID: 19470503 Free PMC article.

8

Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile.

Yang G, Paintsil E, Dutschman GE, Grill SP, Wang CJ, Wang J, Tanaka H, Hamasaki T, Baba M, Cheng YC. Yang G, et al. Among authors: baba m. Antimicrob Agents Chemother. 2009 Nov;53(11):4640-6. doi: 10.1128/AAC.00686-09. Epub 2009 Aug 24. Antimicrob Agents Chemother. 2009. PMID: 19704131 Free PMC article.

9

4'-Ethynylstavudine (4'-Ed4T) has potent anti-HIV-1 activity with reduced toxicity and shows a unique activity profile against drug-resistant mutants.

Tanaka H, Haraguchi K, Kumamoto H, Baba M, Cheng YC. Tanaka H, et al. Among authors: baba m. Antivir Chem Chemother. 2005;16(4):217-21. doi: 10.1177/095632020501600402. Antivir Chem Chemother. 2005. PMID: 16130520 Free article.

10

A new approach to the synthesis of 4'-carbon-substituted nucleosides: development of a highly active anti-HIV agent 2', 3'-didehydro-3'-deoxy-4'-ethynylthymidine.

Haraguchi K, Takeda S, Sumino M, Tanaka H, Dutschman GE, Cheng YC, Nitanda T, Baba M. Haraguchi K, et al. Among authors: baba m. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):343-7. doi: 10.1081/ncn-200059774. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16247949

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