Cheng YC - Search Results

1

Novel 4'-substituted stavudine analog with improved anti-human immunodeficiency virus activity and decreased cytotoxicity.

Dutschman GE, Grill SP, Gullen EA, Haraguchi K, Takeda S, Tanaka H, Baba M, Cheng YC. Dutschman GE, et al. Among authors: cheng yc. Antimicrob Agents Chemother. 2004 May;48(5):1640-6. doi: 10.1128/AAC.48.5.1640-1646.2004. Antimicrob Agents Chemother. 2004. PMID: 15105115 Free PMC article.

2

Reverse transcriptase activity of hepatitis B virus (HBV) DNA polymerase within core capsid: interaction with deoxynucleoside triphosphates and anti-HBV L-deoxynucleoside analog triphosphates.

Lam W, Li Y, Liou JY, Dutschman GE, Cheng YC. Lam W, et al. Among authors: cheng yc. Mol Pharmacol. 2004 Feb;65(2):400-6. doi: 10.1124/mol.65.2.400. Mol Pharmacol. 2004. PMID: 14742682

3

Mechanism of anti-human immunodeficiency virus activity of beta-D-6-cyclopropylamino-2',3'-didehydro-2',3'-dideoxyguanosine.

Ray AS, Hernandez-Santiago BI, Mathew JS, Murakami E, Bozeman C, Xie MY, Dutschman GE, Gullen E, Yang Z, Hurwitz S, Cheng YC, Chu CK, McClure H, Schinazi RF, Anderson KS. Ray AS, et al. Among authors: cheng yc. Antimicrob Agents Chemother. 2005 May;49(5):1994-2001. doi: 10.1128/AAC.49.5.1994-2001.2005. Antimicrob Agents Chemother. 2005. PMID: 15855524 Free PMC article.

4

Behavior of thymidylate kinase toward monophosphate metabolites and its role in the metabolism of 1-(2'-deoxy-2'-fluoro-beta-L-arabinofuranosyl)-5-methyluracil (Clevudine) and 2',3'-didehydro-2',3'-dideoxythymidine in cells.

Hu R, Li L, Degrève B, Dutschman GE, Lam W, Cheng YC. Hu R, et al. Among authors: cheng yc. Antimicrob Agents Chemother. 2005 May;49(5):2044-9. doi: 10.1128/AAC.49.5.2044-2049.2005. Antimicrob Agents Chemother. 2005. PMID: 15855530 Free PMC article.

5

Anti-human immunodeficiency virus type 1 activity and resistance profile of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine in vitro.

Nitanda T, Wang X, Kumamoto H, Haraguchi K, Tanaka H, Cheng YC, Baba M. Nitanda T, et al. Among authors: cheng yc. Antimicrob Agents Chemother. 2005 Aug;49(8):3355-60. doi: 10.1128/AAC.49.8.3355-3360.2005. Antimicrob Agents Chemother. 2005. PMID: 16048947 Free PMC article.

6

Highly selective action of triphosphate metabolite of 4'-ethynyl D4T: a novel anti-HIV compound against HIV-1 RT.

Yang G, Dutschman GE, Wang CJ, Tanaka H, Baba M, Anderson KS, Cheng YC. Yang G, et al. Among authors: cheng yc. Antiviral Res. 2007 Mar;73(3):185-91. doi: 10.1016/j.antiviral.2006.10.002. Epub 2006 Nov 10. Antiviral Res. 2007. PMID: 17109975

7

Comparison of the phosphorylation of 4'-ethynyl 2',3'-dihydro-3'-deoxythymidine with that of other anti-human immunodeficiency virus thymidine analogs.

Hsu CH, Hu R, Dutschman GE, Yang G, Krishnan P, Tanaka H, Baba M, Cheng YC. Hsu CH, et al. Among authors: cheng yc. Antimicrob Agents Chemother. 2007 May;51(5):1687-93. doi: 10.1128/AAC.01432-06. Epub 2007 Mar 12. Antimicrob Agents Chemother. 2007. PMID: 17353236 Free PMC article.

8

Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog.

Paintsil E, Dutschman GE, Hu R, Grill SP, Lam W, Baba M, Tanaka H, Cheng YC. Paintsil E, et al. Among authors: cheng yc. Antimicrob Agents Chemother. 2007 Nov;51(11):3870-9. doi: 10.1128/AAC.00692-07. Epub 2007 Aug 27. Antimicrob Agents Chemother. 2007. PMID: 17724147 Free PMC article.

9

Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase by a stavudine analogue, 4'-ethynyl stavudine triphosphate.

Yang G, Wang J, Cheng Y, Dutschman GE, Tanaka H, Baba M, Cheng YC. Yang G, et al. Among authors: cheng y, cheng yc. Antimicrob Agents Chemother. 2008 Jun;52(6):2035-42. doi: 10.1128/AAC.00083-08. Epub 2008 Apr 7. Antimicrob Agents Chemother. 2008. PMID: 18391035 Free PMC article.

10

Retention of metabolites of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel anti-human immunodeficiency virus type 1 thymidine analog, in cells.

Wang X, Tanaka H, Baba M, Cheng YC. Wang X, et al. Among authors: cheng yc. Antimicrob Agents Chemother. 2009 Aug;53(8):3317-24. doi: 10.1128/AAC.00302-09. Epub 2009 May 26. Antimicrob Agents Chemother. 2009. PMID: 19470503 Free PMC article.

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