Grill SP - Search Results

1

Novel 4'-substituted stavudine analog with improved anti-human immunodeficiency virus activity and decreased cytotoxicity.

Dutschman GE, Grill SP, Gullen EA, Haraguchi K, Takeda S, Tanaka H, Baba M, Cheng YC. Dutschman GE, et al. Among authors: grill sp. Antimicrob Agents Chemother. 2004 May;48(5):1640-6. doi: 10.1128/AAC.48.5.1640-1646.2004. Antimicrob Agents Chemother. 2004. PMID: 15105115 Free PMC article.

2

Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog.

Paintsil E, Dutschman GE, Hu R, Grill SP, Lam W, Baba M, Tanaka H, Cheng YC. Paintsil E, et al. Among authors: grill sp. Antimicrob Agents Chemother. 2007 Nov;51(11):3870-9. doi: 10.1128/AAC.00692-07. Epub 2007 Aug 27. Antimicrob Agents Chemother. 2007. PMID: 17724147 Free PMC article.

3

Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile.

Yang G, Paintsil E, Dutschman GE, Grill SP, Wang CJ, Wang J, Tanaka H, Hamasaki T, Baba M, Cheng YC. Yang G, et al. Among authors: grill sp. Antimicrob Agents Chemother. 2009 Nov;53(11):4640-6. doi: 10.1128/AAC.00686-09. Epub 2009 Aug 24. Antimicrob Agents Chemother. 2009. PMID: 19704131 Free PMC article.

4

A novel class of meso-tetrakis-porphyrin derivatives exhibits potent activities against hepatitis C virus genotype 1b replicons in vitro.

Cheng Y, Tsou LK, Cai J, Aya T, Dutschman GE, Gullen EA, Grill SP, Chen AP, Lindenbach BD, Hamilton AD, Cheng YC. Cheng Y, et al. Among authors: grill sp. Antimicrob Agents Chemother. 2010 Jan;54(1):197-206. doi: 10.1128/AAC.01206-09. Epub 2009 Nov 9. Antimicrob Agents Chemother. 2010. PMID: 19901090 Free PMC article.

5

Determinants of individual variation in intracellular accumulation of anti-HIV nucleoside analog metabolites.

Paintsil E, Dutschman GE, Hu R, Grill SP, Wang CJ, Lam W, Li FY, Ghebremichael M, Northrup V, Cheng YC. Paintsil E, et al. Among authors: grill sp. Antimicrob Agents Chemother. 2011 Feb;55(2):895-903. doi: 10.1128/AAC.01303-10. Epub 2010 Nov 15. Antimicrob Agents Chemother. 2011. PMID: 21078952 Free PMC article.

6

Anti-herpes simplex virus activity of 5-substituted 2-pyrimidinone nucleosides.

Lewandowski GA, Grill SP, Fisher MH, Dutschman GE, Efange SM, Bardos TJ, Cheng YC. Lewandowski GA, et al. Among authors: grill sp. Antimicrob Agents Chemother. 1989 Mar;33(3):340-4. doi: 10.1128/AAC.33.3.340. Antimicrob Agents Chemother. 1989. PMID: 2543279 Free PMC article.

7

Metabolism and mode of inhibition of varicella-zoster virus by L-beta-5-bromovinyl-(2-hydroxymethyl)-(1,3-dioxolanyl)uracil is dependent on viral thymidine kinase.

Li L, Dutschman GE, Gullen EA, Tsujii E, Grill SP, Choi Y, Chu CK, Cheng YC. Li L, et al. Among authors: grill sp. Mol Pharmacol. 2000 Nov;58(5):1109-14. doi: 10.1124/mol.58.5.1109. Mol Pharmacol. 2000. PMID: 11040060

8

Anti-Epstein-Barr virus (EBV) activity of beta-L-5-iododioxolane uracil is dependent on EBV thymidine kinase.

Kira T, Grill SP, Dutschman GE, Lin JS, Qu F, Choi Y, Chu CK, Cheng YC. Kira T, et al. Among authors: grill sp. Antimicrob Agents Chemother. 2000 Dec;44(12):3278-84. doi: 10.1128/AAC.44.12.3278-3284.2000. Antimicrob Agents Chemother. 2000. PMID: 11083627 Free PMC article.

9

Novel role of 3-phosphoglycerate kinase, a glycolytic enzyme, in the activation of L-nucleoside analogs, a new class of anticancer and antiviral agents.

Krishnan P, Gullen EA, Lam W, Dutschman GE, Grill SP, Cheng YC. Krishnan P, et al. Among authors: grill sp. J Biol Chem. 2003 Sep 19;278(38):36726-32. doi: 10.1074/jbc.M307052200. Epub 2003 Jul 16. J Biol Chem. 2003. PMID: 12869554 Free article.

10

Comparative study of the persistence of anti-HIV activity of deoxynucleoside HIV reverse transcriptase inhibitors after removal from culture.

Paintsil E, Grill SP, Dutschman GE, Cheng YC. Paintsil E, et al. Among authors: grill sp. AIDS Res Ther. 2009 Apr 22;6:5. doi: 10.1186/1742-6405-6-5. AIDS Res Ther. 2009. PMID: 19386130 Free PMC article.

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