Medcalf R - Search Results

1

Novel inhibitors of urokinase-type plasminogen activator and matrix metalloproteinase expression in metastatic cancer cell lines.

Cakarovski K, Leung JY, Restall C, Carin-Carlson A, Yang E, Perlmutter P, Anderson R, Medcalf R, Dear AE. Cakarovski K, et al. Among authors: medcalf r. Int J Cancer. 2004 Jul 1;110(4):610-6. doi: 10.1002/ijc.20135. Int J Cancer. 2004. PMID: 15122596

2

Urokinase-type plasminogen activator biosynthesis is induced by the EJ-Ha-ras oncogene in CL26 mouse colon carcinoma cells.

Testa JE, Medcalf RL, Cajot JF, Schleuning WD, Sordat B. Testa JE, et al. Among authors: medcalf rl. Int J Cancer. 1989 May 15;43(5):816-22. doi: 10.1002/ijc.2910430513. Int J Cancer. 1989. PMID: 2497073

3

Plasminogen activator inhibitor type 2 gene induction by tumor necrosis factor and phorbol ester involves transcriptional and post-transcriptional events. Identification of a functional nonameric AU-rich motif in the 3'-untranslated region.

Maurer F, Medcalf RL. Maurer F, et al. Among authors: medcalf rl. J Biol Chem. 1996 Oct 18;271(42):26074-80. doi: 10.1074/jbc.271.42.26074. J Biol Chem. 1996. PMID: 8824249 Free article.

4

Molecular mechanisms governing tumor-necrosis-factor-mediated regulation of plasminogen-activator inhibitor type-2 gene expression.

Dear AE, Shen Y, Rüegg M, Medcalf RL. Dear AE, et al. Among authors: medcalf rl. Eur J Biochem. 1996 Oct 1;241(1):93-100. doi: 10.1111/j.1432-1033.1996.0093t.x. Eur J Biochem. 1996. PMID: 8898893 Free article.

5

Urokinase-mediated transactivation of the plasminogen activator inhibitor type 2 (PAI-2) gene promoter in HT-1080 cells utilises AP-1 binding sites and potentiates phorbol ester-mediated induction of endogenous PAI-2 mRNA.

Dear AE, Costa M, Medcalf RL. Dear AE, et al. Among authors: medcalf rl. FEBS Lett. 1997 Feb 3;402(2-3):265-72. doi: 10.1016/s0014-5793(97)00002-1. FEBS Lett. 1997. PMID: 9037208 Free article.

6

The urokinase-type-plasminogen-activator receptor (CD87) is a pleiotropic molecule.

Dear AE, Medcalf RL. Dear AE, et al. Among authors: medcalf rl. Eur J Biochem. 1998 Mar 1;252(2):185-93. doi: 10.1046/j.1432-1327.1998.2520185.x. Eur J Biochem. 1998. PMID: 9523687 Free article. Review.

7

Transcriptional regulation of the tissue-type plasminogen-activator gene in human endothelial cells: identification of nuclear factors that recognise functional elements in the tissue-type plasminogen-activator gene promoter.

Costa M, Shen Y, Maurer F, Medcalf RL. Costa M, et al. Among authors: medcalf rl. Eur J Biochem. 1998 Nov 15;258(1):123-31. doi: 10.1046/j.1432-1327.1998.2580123.x. Eur J Biochem. 1998. PMID: 9851700 Free article.

8

An AU-rich sequence in the 3'-UTR of plasminogen activator inhibitor type 2 (PAI-2) mRNA promotes PAI-2 mRNA decay and provides a binding site for nuclear HuR.

Maurer F, Tierney M, Medcalf RL. Maurer F, et al. Among authors: medcalf rl. Nucleic Acids Res. 1999 Apr 1;27(7):1664-73. doi: 10.1093/nar/27.7.1664. Nucleic Acids Res. 1999. PMID: 10075998 Free PMC article.

9

The novel anti-tumour agent oxamflatin differentially regulates urokinase and plasminogen activator inhibitor type 2 expression and inhibits urokinase-mediated proteolytic activity.

Dear AE, Medcalf RL. Dear AE, et al. Among authors: medcalf rl. Biochim Biophys Acta. 2000 Jun 21;1492(1):15-22. doi: 10.1016/s0167-4781(00)00041-5. Biochim Biophys Acta. 2000. PMID: 11004477

10

Overexpression of a dominant negative CREB protein in HT-1080 cells selectively disrupts plasminogen activator inhibitor type 2 but not tissue-type plasminogen activator gene expression.

Costa M, Shen Y, Medcalf RL. Costa M, et al. Among authors: medcalf rl. FEBS Lett. 2000 Sep 29;482(1-2):75-80. doi: 10.1016/s0014-5793(00)02030-5. FEBS Lett. 2000. PMID: 11018526 Free article.

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