Kerns EH - Search Results

1

Combined application of parallel artificial membrane permeability assay and Caco-2 permeability assays in drug discovery.

Kerns EH, Di L, Petusky S, Farris M, Ley R, Jupp P. Kerns EH, et al. J Pharm Sci. 2004 Jun;93(6):1440-53. doi: 10.1002/jps.20075. J Pharm Sci. 2004. PMID: 15124203

2

Multivariate pharmaceutical profiling for drug discovery.

Kerns EH, Di L. Kerns EH, et al. Curr Top Med Chem. 2002 Jan;2(1):87-98. doi: 10.2174/1568026023394470. Curr Top Med Chem. 2002. PMID: 11899067 Review.

3

Pharmaceutical profiling in drug discovery.

Kerns EH, Di L. Kerns EH, et al. Drug Discov Today. 2003 Apr 1;8(7):316-23. doi: 10.1016/s1359-6446(03)02649-7. Drug Discov Today. 2003. PMID: 12654544

4

High throughput artificial membrane permeability assay for blood-brain barrier.

Di L, Kerns EH, Fan K, McConnell OJ, Carter GT. Di L, et al. Among authors: kerns eh. Eur J Med Chem. 2003 Mar;38(3):223-32. doi: 10.1016/s0223-5234(03)00012-6. Eur J Med Chem. 2003. PMID: 12667689

5

Integrated high capacity solid phase extraction-MS/MS system for pharmaceutical profiling in drug discovery.

Kerns EH, Kleintop T, Little D, Tobien T, Mallis L, Di L, Hu M, Hong Y, McConnell OJ. Kerns EH, et al. J Pharm Biomed Anal. 2004 Jan 27;34(1):1-9. doi: 10.1016/j.japna.2003.03.001. J Pharm Biomed Anal. 2004. PMID: 14738913

6

Experimental design on single-time-point high-throughput microsomal stability assay.

Di L, Kerns EH, Gao N, Li SQ, Huang Y, Bourassa JL, Huryn DM. Di L, et al. Among authors: kerns eh. J Pharm Sci. 2004 Jun;93(6):1537-44. doi: 10.1002/jps.20076. J Pharm Sci. 2004. PMID: 15124211

7

Application of pharmaceutical profiling assays for optimization of drug-like properties.

Di L, Kerns EH. Di L, et al. Among authors: kerns eh. Curr Opin Drug Discov Devel. 2005 Jul;8(4):495-504. Curr Opin Drug Discov Devel. 2005. PMID: 16022186 Review.

8

Utility of mass spectrometry for pharmaceutical profiling applications.

Kerns EH, Di L. Kerns EH, et al. Curr Drug Metab. 2006 Jun;7(5):457-66. doi: 10.2174/138920006777697981. Curr Drug Metab. 2006. PMID: 16787155 Review.

9

Comparison of blood-brain barrier permeability assays: in situ brain perfusion, MDR1-MDCKII and PAMPA-BBB.

Di L, Kerns EH, Bezar IF, Petusky SL, Huang Y. Di L, et al. Among authors: kerns eh. J Pharm Sci. 2009 Jun;98(6):1980-91. doi: 10.1002/jps.21580. J Pharm Sci. 2009. PMID: 18837012

10

In vitro solubility assays in drug discovery.

Kerns EH, Di L, Carter GT. Kerns EH, et al. Curr Drug Metab. 2008 Nov;9(9):879-85. doi: 10.2174/138920008786485100. Curr Drug Metab. 2008. PMID: 18991584 Review.

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