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Absence of a reductase, NCB5OR, causes insulin-deficient diabetes.
Xie J, Zhu H, Larade K, Ladoux A, Seguritan A, Chu M, Ito S, Bronson RT, Leiter EH, Zhang CY, Rosen ED, Bunn HF. Xie J, et al. Among authors: zhu h. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10750-5. doi: 10.1073/pnas.0404044101. Epub 2004 Jul 9. Proc Natl Acad Sci U S A. 2004. PMID: 15247412 Free PMC article.
Detecting and responding to hypoxia.
Zhu H, Jackson T, Bunn HF. Zhu H, et al. Nephrol Dial Transplant. 2002;17 Suppl 1(Suppl 1):3-7. doi: 10.1093/ndt/17.suppl_1.3. Nephrol Dial Transplant. 2002. PMID: 11812905 Free PMC article. Review.
Signal transduction. How do cells sense oxygen?
Zhu H, Bunn HF. Zhu H, et al. Science. 2001 Apr 20;292(5516):449-51. doi: 10.1126/science.1060849. Epub 2001 Apr 5. Science. 2001. PMID: 11292863 Free PMC article.
Development of diabetes in lean Ncb5or-null mice is associated with manifestations of endoplasmic reticulum and oxidative stress in beta cells.
Wang W, Guo Y, Xu M, Huang HH, Novikova L, Larade K, Jiang ZG, Thayer TC, Frontera JR, Aires D, Ding H, Turk J, Mathews CE, Bunn HF, Stehno-Bittel L, Zhu H. Wang W, et al. Among authors: zhu h. Biochim Biophys Acta. 2011 Nov;1812(11):1532-41. doi: 10.1016/j.bbadis.2011.07.016. Epub 2011 Aug 2. Biochim Biophys Acta. 2011. PMID: 21839170 Free PMC article.
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