Role of receptor-mediated endocytosis, endosomal acidification and cathepsin D in cholera toxin cytotoxicity.
El Hage T, Merlen C, Fabrega S, Authier F.
El Hage T, et al. Among authors: merlen c.
FEBS J. 2007 May;274(10):2614-29. doi: 10.1111/j.1742-4658.2007.05797.x. Epub 2007 Apr 19.
FEBS J. 2007.
PMID: 17451437
Free article.
Using the in situ liver model system, we have recently shown that, after cholera toxin binding to hepatic cells, cholera toxin accumulates in a low-density endosomal compartment, and then undergoes endosomal proteolysis by the aspartic acid protease cathepsin-D [Merlen …
Using the in situ liver model system, we have recently shown that, after cholera toxin binding to hepatic cells, cholera toxin accumulates i …