Patel SB - Search Results

1

Crystal structure of human phosphodiesterase 3B: atomic basis for substrate and inhibitor specificity.

Scapin G, Patel SB, Chung C, Varnerin JP, Edmondson SD, Mastracchio A, Parmee ER, Singh SB, Becker JW, Van der Ploeg LH, Tota MR. Scapin G, et al. Among authors: patel sb. Biochemistry. 2004 May 25;43(20):6091-100. doi: 10.1021/bi049868i. Biochemistry. 2004. PMID: 15147193

2

The structural basis for the selectivity of benzotriazole inhibitors of PTP1B.

Scapin G, Patel SB, Becker JW, Wang Q, Desponts C, Waddleton D, Skorey K, Cromlish W, Bayly C, Therien M, Gauthier JY, Li CS, Lau CK, Ramachandran C, Kennedy BP, Asante-Appiah E. Scapin G, et al. Among authors: patel sb. Biochemistry. 2003 Oct 7;42(39):11451-9. doi: 10.1021/bi035098j. Biochemistry. 2003. PMID: 14516196

3

Crystallization and preliminary X-ray diffraction analysis of the catalytic domain of recombinant human phosphodiesterase 3B.

Patel SB, Varnerin JP, Tota MR, Edmondson SD, Parmee ER, Becker JW, Scapin G. Patel SB, et al. Acta Crystallogr D Biol Crystallogr. 2004 Jan;60(Pt 1):169-71. doi: 10.1107/s0907444903025101. Epub 2003 Dec 18. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 14684919

4

Expression, refolding, and purification of recombinant human phosphodiesterase 3B: definition of the N-terminus of the catalytic core.

Varnerin JP, Chung CC, Patel SB, Scapin G, Parmee ER, Morin NR, MacNeil DJ, Cully DF, Van der Ploeg LH, Tota MR. Varnerin JP, et al. Among authors: patel sb. Protein Expr Purif. 2004 Jun;35(2):225-36. doi: 10.1016/j.pep.2004.01.009. Protein Expr Purif. 2004. PMID: 15135397

5

The role of tryptophan 1072 in human PDE3B inhibitor binding.

Chung C, Varnerin JP, Morin NR, MacNeil DJ, Singh SB, Patel S, Scapin G, Van der Ploeg LH, Tota MR. Chung C, et al. Among authors: patel s. Biochem Biophys Res Commun. 2003 Aug 8;307(4):1045-50. doi: 10.1016/s0006-291x(03)01299-3. Biochem Biophys Res Commun. 2003. PMID: 12878217

6

Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity.

Fitzgerald CE, Patel SB, Becker JW, Cameron PM, Zaller D, Pikounis VB, O'Keefe SJ, Scapin G. Fitzgerald CE, et al. Among authors: patel sb. Nat Struct Biol. 2003 Sep;10(9):764-9. doi: 10.1038/nsb949. Epub 2003 Aug 3. Nat Struct Biol. 2003. PMID: 12897767

7

The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity.

Scapin G, Patel SB, Lisnock J, Becker JW, LoGrasso PV. Scapin G, et al. Among authors: patel sb. Chem Biol. 2003 Aug;10(8):705-12. doi: 10.1016/s1074-5521(03)00159-5. Chem Biol. 2003. PMID: 12954329

8

The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates.

Asante-Appiah E, Patel S, Dufresne C, Roy P, Wang Q, Patel V, Friesen RW, Ramachandran C, Becker JW, Leblanc Y, Kennedy BP, Scapin G. Asante-Appiah E, et al. Biochemistry. 2002 Jul 23;41(29):9043-51. doi: 10.1021/bi0259554. Biochemistry. 2002. PMID: 12119018

9

The structure of apo protein-tyrosine phosphatase 1B C215S mutant: more than just an S --> O change.

Scapin G, Patel S, Patel V, Kennedy B, Asante-Appiah E. Scapin G, et al. Protein Sci. 2001 Aug;10(8):1596-605. doi: 10.1110/ps.11001. Protein Sci. 2001. PMID: 11468356 Free PMC article.

10

Lattice stabilization and enhanced diffraction in human p38 alpha crystals by protein engineering.

Patel SB, Cameron PM, Frantz-Wattley B, O'Neill E, Becker JW, Scapin G. Patel SB, et al. Biochim Biophys Acta. 2004 Jan 14;1696(1):67-73. doi: 10.1016/j.bbapap.2003.09.009. Biochim Biophys Acta. 2004. PMID: 14726206

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