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14 results

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Page 1
Benzyl vinylogous amide substituted aryldihydropyridazinones and aryldimethylpyrazolones as potent and selective PDE3B inhibitors.
Edmondson SD, Mastracchio A, He J, Chung CC, Forrest MJ, Hofsess S, MacIntyre E, Metzger J, O'Connor N, Patel K, Tong X, Tota MR, Van der Ploeg LH, Varnerin JP, Fisher MH, Wyvratt MJ, Weber AE, Parmee ER. Edmondson SD, et al. Among authors: varnerin jp. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3983-7. doi: 10.1016/j.bmcl.2003.08.056. Bioorg Med Chem Lett. 2003. PMID: 14592490
The role of tryptophan 1072 in human PDE3B inhibitor binding.
Chung C, Varnerin JP, Morin NR, MacNeil DJ, Singh SB, Patel S, Scapin G, Van der Ploeg LH, Tota MR. Chung C, et al. Among authors: varnerin jp. Biochem Biophys Res Commun. 2003 Aug 8;307(4):1045-50. doi: 10.1016/s0006-291x(03)01299-3. Biochem Biophys Res Commun. 2003. PMID: 12878217
Localization of leptin binding domain in the leptin receptor.
Fong TM, Huang RR, Tota MR, Mao C, Smith T, Varnerin J, Karpitskiy VV, Krause JE, Van der Ploeg LH. Fong TM, et al. Mol Pharmacol. 1998 Feb;53(2):234-40. doi: 10.1124/mol.53.2.234. Mol Pharmacol. 1998. PMID: 9463481
A fluorescence-based thiol quantification assay for ultra-high-throughput screening for inhibitors of coenzyme A production.
Chung CC, Ohwaki K, Schneeweis JE, Stec E, Varnerin JP, Goudreau PN, Chang A, Cassaday J, Yang L, Yamakawa T, Kornienko O, Hodder P, Inglese J, Ferrer M, Strulovici B, Kusunoki J, Tota MR, Takagi T. Chung CC, et al. Among authors: varnerin jp. Assay Drug Dev Technol. 2008 Jun;6(3):361-74. doi: 10.1089/adt.2007.105. Assay Drug Dev Technol. 2008. PMID: 18452391
A rapid, quantitative functional assay for measuring leptin.
Rosenblum CI, Vongs A, Tota MR, Varnerin JP, Frazier E, Cully DF, Morsy MA, Van der Ploeg LH. Rosenblum CI, et al. Among authors: varnerin jp. Mol Cell Endocrinol. 1998 Aug 25;143(1-2):117-23. doi: 10.1016/s0303-7207(98)00129-4. Mol Cell Endocrinol. 1998. PMID: 9806356
3-Aryl-4-hydroxyquinolin-2(1H)-one derivatives as type I fatty acid synthase inhibitors.
Rivkin A, Kim YR, Goulet MT, Bays N, Hill AD, Kariv I, Krauss S, Ginanni N, Strack PR, Kohl NE, Chung CC, Varnerin JP, Goudreau PN, Chang A, Tota MR, Munoz B. Rivkin A, et al. Among authors: varnerin jp. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4620-3. doi: 10.1016/j.bmcl.2006.06.014. Epub 2006 Jun 19. Bioorg Med Chem Lett. 2006. PMID: 16784844
Production of leptin in Escherichia coli: a comparison of methods.
Varnerin JP, Smith T, Rosenblum CI, Vongs A, Murphy BA, Nunes C, Mellin TN, King JJ, Burgess BW, Junker B, Chou M, Hey P, Frazier E, MacIntyre DE, Van der Ploeg LH, Tota MR. Varnerin JP, et al. Protein Expr Purif. 1998 Dec;14(3):335-42. doi: 10.1006/prep.1998.0978. Protein Expr Purif. 1998. PMID: 9882567
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