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Combined functional and molecular analysis of tumor cell signaling defines 2 distinct myeloma subgroups: Akt-dependent and Akt-independent multiple myeloma.
Zöllinger A, Stühmer T, Chatterjee M, Gattenlöhner S, Haralambieva E, Müller-Hermelink HK, Andrulis M, Greiner A, Wesemeier C, Rath JC, Einsele H, Bargou RC. Zöllinger A, et al. Among authors: andrulis m. Blood. 2008 Oct 15;112(8):3403-11. doi: 10.1182/blood-2007-11-119362. Epub 2008 Jul 17. Blood. 2008. PMID: 18635812 Free article.
STAT3 and MAPK signaling maintain overexpression of heat shock proteins 90alpha and beta in multiple myeloma cells, which critically contribute to tumor-cell survival.
Chatterjee M, Jain S, Stühmer T, Andrulis M, Ungethüm U, Kuban RJ, Lorentz H, Bommert K, Topp M, Krämer D, Müller-Hermelink HK, Einsele H, Greiner A, Bargou RC. Chatterjee M, et al. Among authors: andrulis m. Blood. 2007 Jan 15;109(2):720-8. doi: 10.1182/blood-2006-05-024372. Epub 2006 Sep 26. Blood. 2007. PMID: 17003370 Free article.
Integrin-linked kinase is dispensable for multiple myeloma cell survival.
Steinbrunn T, Siegmund D, Andrulis M, Grella E, Kortüm M, Einsele H, Wajant H, Bargou RC, Stühmer T. Steinbrunn T, et al. Among authors: andrulis m. Leuk Res. 2012 Sep;36(9):1165-71. doi: 10.1016/j.leukres.2012.05.005. Epub 2012 Jun 1. Leuk Res. 2012. PMID: 22658851
70 results