Greschik H - Search Results

1

Structural basis for the deactivation of the estrogen-related receptor gamma by diethylstilbestrol or 4-hydroxytamoxifen and determinants of selectivity.

Greschik H, Flaig R, Renaud JP, Moras D. Greschik H, et al. J Biol Chem. 2004 Aug 6;279(32):33639-46. doi: 10.1074/jbc.M402195200. Epub 2004 May 24. J Biol Chem. 2004. PMID: 15161930 Free article.

2

Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3.

Greschik H, Wurtz JM, Sanglier S, Bourguet W, van Dorsselaer A, Moras D, Renaud JP. Greschik H, et al. Mol Cell. 2002 Feb;9(2):303-13. doi: 10.1016/s1097-2765(02)00444-6. Mol Cell. 2002. PMID: 11864604 Free article.

3

Structure-activity relationship of nuclear receptor-ligand interactions.

Greschik H, Moras D. Greschik H, et al. Curr Top Med Chem. 2003;3(14):1573-99. doi: 10.2174/1568026033451736. Curr Top Med Chem. 2003. PMID: 14683516 Review.

4

Structural basis for the cell-specific activities of the NGFI-B and the Nurr1 ligand-binding domain.

Flaig R, Greschik H, Peluso-Iltis C, Moras D. Flaig R, et al. Among authors: greschik h. J Biol Chem. 2005 May 13;280(19):19250-8. doi: 10.1074/jbc.M413175200. Epub 2005 Feb 16. J Biol Chem. 2005. PMID: 15716272 Free article.

5

Communication between the ERRalpha homodimer interface and the PGC-1alpha binding surface via the helix 8-9 loop.

Greschik H, Althage M, Flaig R, Sato Y, Chavant V, Peluso-Iltis C, Choulier L, Cronet P, Rochel N, Schüle R, Strömstedt PE, Moras D. Greschik H, et al. J Biol Chem. 2008 Jul 18;283(29):20220-30. doi: 10.1074/jbc.M801920200. Epub 2008 Apr 25. J Biol Chem. 2008. PMID: 18441008 Free article.

6

Characterization of the DNA-binding and dimerization properties of the nuclear orphan receptor germ cell nuclear factor.

Greschik H, Wurtz JM, Hublitz P, Köhler F, Moras D, Schüle R. Greschik H, et al. Mol Cell Biol. 1999 Jan;19(1):690-703. doi: 10.1128/MCB.19.1.690. Mol Cell Biol. 1999. PMID: 9858592 Free PMC article.

7

KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells.

Metzger E, Wang S, Urban S, Willmann D, Schmidt A, Offermann A, Allen A, Sum M, Obier N, Cottard F, Ulferts S, Preca BT, Hermann B, Maurer J, Greschik H, Hornung V, Einsle O, Perner S, Imhof A, Jung M, Schüle R. Metzger E, et al. Among authors: greschik h. Nat Struct Mol Biol. 2019 May;26(5):361-371. doi: 10.1038/s41594-019-0219-9. Epub 2019 May 6. Nat Struct Mol Biol. 2019. PMID: 31061526

8

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4.

Metzger E, Imhof A, Patel D, Kahl P, Hoffmeyer K, Friedrichs N, Müller JM, Greschik H, Kirfel J, Ji S, Kunowska N, Beisenherz-Huss C, Günther T, Buettner R, Schüle R. Metzger E, et al. Among authors: greschik h. Nature. 2010 Apr 1;464(7289):792-6. doi: 10.1038/nature08839. Epub 2010 Mar 14. Nature. 2010. PMID: 20228790

9

Structure-Based Design, Docking and Binding Free Energy Calculations of A366 Derivatives as Spindlin1 Inhibitors.

Luise C, Robaa D, Regenass P, Maurer D, Ostrovskyi D, Seifert L, Bacher J, Burgahn T, Wagner T, Seitz J, Greschik H, Park KS, Xiong Y, Jin J, Schüle R, Breit B, Jung M, Sippl W. Luise C, et al. Among authors: greschik h. Int J Mol Sci. 2021 May 31;22(11):5910. doi: 10.3390/ijms22115910. Int J Mol Sci. 2021. PMID: 34072837 Free PMC article.

10

Selective targeting of epigenetic reader domains.

Greschik H, Schüle R, Günther T. Greschik H, et al. Expert Opin Drug Discov. 2017 May;12(5):449-463. doi: 10.1080/17460441.2017.1303474. Epub 2017 Mar 14. Expert Opin Drug Discov. 2017. PMID: 28277835 Review.

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