Gut J - Search Results

1

Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi.

Greenbaum DC, Mackey Z, Hansell E, Doyle P, Gut J, Caffrey CR, Lehrman J, Rosenthal PJ, McKerrow JH, Chibale K. Greenbaum DC, et al. Among authors: gut j. J Med Chem. 2004 Jun 3;47(12):3212-9. doi: 10.1021/jm030549j. J Med Chem. 2004. PMID: 15163200

2

Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3.

Sijwali PS, Shenai BR, Gut J, Singh A, Rosenthal PJ. Sijwali PS, et al. Among authors: gut j. Biochem J. 2001 Dec 1;360(Pt 2):481-9. doi: 10.1042/0264-6021:3600481. Biochem J. 2001. PMID: 11716777 Free PMC article.

3

Critical role of amino acid 23 in mediating activity and specificity of vinckepain-2, a papain-family cysteine protease of rodent malaria parasites.

Singh A, Shenai BR, Choe Y, Gut J, Sijwali PS, Craik CS, Rosenthal PJ. Singh A, et al. Among authors: gut j. Biochem J. 2002 Nov 15;368(Pt 1):273-81. doi: 10.1042/BJ20020753. Biochem J. 2002. PMID: 12169096 Free PMC article.

4

Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain.

Chiyanzu I, Hansell E, Gut J, Rosenthal PJ, McKerrow JH, Chibale K. Chiyanzu I, et al. Among authors: gut j. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3527-30. doi: 10.1016/s0960-894x(03)00756-x. Bioorg Med Chem Lett. 2003. PMID: 14505663

5

Composition and anti-plasmodial activities of essential oils from some Cameroonian medicinal plants.

Boyom FF, Ngouana V, Zollo PH, Menut C, Bessiere JM, Gut J, Rosenthal PJ. Boyom FF, et al. Among authors: gut j. Phytochemistry. 2003 Dec;64(7):1269-75. doi: 10.1016/j.phytochem.2003.08.004. Phytochemistry. 2003. PMID: 14599525

6

5HT1A serotonin receptor agonists inhibit Plasmodium falciparum by blocking a membrane channel.

Locher CP, Ruben PC, Gut J, Rosenthal PJ. Locher CP, et al. Among authors: gut j. Antimicrob Agents Chemother. 2003 Dec;47(12):3806-9. doi: 10.1128/AAC.47.12.3806-3809.2003. Antimicrob Agents Chemother. 2003. PMID: 14638487 Free PMC article.

7

Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites.

Sijwali PS, Kato K, Seydel KB, Gut J, Lehman J, Klemba M, Goldberg DE, Miller LH, Rosenthal PJ. Sijwali PS, et al. Among authors: gut j. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8721-6. doi: 10.1073/pnas.0402738101. Epub 2004 May 27. Proc Natl Acad Sci U S A. 2004. PMID: 15166288 Free PMC article.

8

Application of multi-component reactions to antimalarial drug discovery. Part 1: Parallel synthesis and antiplasmodial activity of new 4-aminoquinoline Ugi adducts.

Musonda CC, Taylor D, Lehman J, Gut J, Rosenthal PJ, Chibale K. Musonda CC, et al. Among authors: gut j. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3901-5. doi: 10.1016/j.bmcl.2004.05.063. Bioorg Med Chem Lett. 2004. PMID: 15225694

9

Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain.

Fujii N, Mallari JP, Hansell EJ, Mackey Z, Doyle P, Zhou YM, Gut J, Rosenthal PJ, McKerrow JH, Guy RK. Fujii N, et al. Among authors: gut j. Bioorg Med Chem Lett. 2005 Jan 3;15(1):121-3. doi: 10.1016/j.bmcl.2004.10.023. Bioorg Med Chem Lett. 2005. PMID: 15582423

10

Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database.

Desai PV, Patny A, Sabnis Y, Tekwani B, Gut J, Rosenthal P, Srivastava A, Avery M. Desai PV, et al. Among authors: gut j. J Med Chem. 2004 Dec 16;47(26):6609-15. doi: 10.1021/jm0493717. J Med Chem. 2004. PMID: 15588096

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