Li J - Search Results

1

Cross-talk between thiamin diphosphate binding and phosphorylation loop conformation in human branched-chain alpha-keto acid decarboxylase/dehydrogenase.

Li J, Wynn RM, Machius M, Chuang JL, Karthikeyan S, Tomchick DR, Chuang DT. Li J, et al. J Biol Chem. 2004 Jul 30;279(31):32968-78. doi: 10.1074/jbc.M403611200. Epub 2004 May 27. J Biol Chem. 2004. PMID: 15166214 Free article.

2

Encapsulation of an 86-kDa assembly intermediate inside the cavities of GroEL and its single-ring variant SR1 by GroES.

Song JL, Li J, Huang YS, Chuang DT. Song JL, et al. Among authors: li j. J Biol Chem. 2003 Jan 24;278(4):2515-21. doi: 10.1074/jbc.M209705200. Epub 2002 Nov 12. J Biol Chem. 2003. PMID: 12431983 Free article.

3

Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase: refined phosphorylation loop structure in the active site.

Wynn RM, Machius M, Chuang JL, Li J, Tomchick DR, Chuang DT. Wynn RM, et al. Among authors: li j. J Biol Chem. 2003 Oct 31;278(44):43402-10. doi: 10.1074/jbc.M306204200. Epub 2003 Aug 5. J Biol Chem. 2003. PMID: 12902323 Free article.

4

Structural and biochemical basis for novel mutations in homozygous Israeli maple syrup urine disease patients: a proposed mechanism for the thiamin-responsive phenotype.

Chuang JL, Wynn RM, Moss CC, Song JL, Li J, Awad N, Mandel H, Chuang DT. Chuang JL, et al. Among authors: li j. J Biol Chem. 2004 Apr 23;279(17):17792-800. doi: 10.1074/jbc.M313879200. Epub 2004 Jan 23. J Biol Chem. 2004. PMID: 14742428 Free article.

5

Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation.

Wynn RM, Kato M, Machius M, Chuang JL, Li J, Tomchick DR, Chuang DT. Wynn RM, et al. Among authors: li j. Structure. 2004 Dec;12(12):2185-96. doi: 10.1016/j.str.2004.09.013. Structure. 2004. PMID: 15576032 Free article.

6

A versatile conformational switch regulates reactivity in human branched-chain alpha-ketoacid dehydrogenase.

Machius M, Wynn RM, Chuang JL, Li J, Kluger R, Yu D, Tomchick DR, Brautigam CA, Chuang DT. Machius M, et al. Among authors: li j. Structure. 2006 Feb;14(2):287-98. doi: 10.1016/j.str.2005.10.009. Structure. 2006. PMID: 16472748 Free article.

7

The two active sites in human branched-chain alpha-keto acid dehydrogenase operate independently without an obligatory alternating-site mechanism.

Li J, Machius M, Chuang JL, Wynn RM, Chuang DT. Li J, et al. J Biol Chem. 2007 Apr 20;282(16):11904-13. doi: 10.1074/jbc.M610843200. Epub 2007 Feb 27. J Biol Chem. 2007. PMID: 17329260 Free article.

8

Pyruvate dehydrogenase kinase-4 structures reveal a metastable open conformation fostering robust core-free basal activity.

Wynn RM, Kato M, Chuang JL, Tso SC, Li J, Chuang DT. Wynn RM, et al. Among authors: li j. J Biol Chem. 2008 Sep 12;283(37):25305-25315. doi: 10.1074/jbc.M802249200. Epub 2008 Jul 24. J Biol Chem. 2008. PMID: 18658136 Free PMC article.

9

Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops.

Kato M, Wynn RM, Chuang JL, Tso SC, Machius M, Li J, Chuang DT. Kato M, et al. Among authors: li j. Structure. 2008 Dec 10;16(12):1849-59. doi: 10.1016/j.str.2008.10.010. Structure. 2008. PMID: 19081061 Free PMC article.

10

Pivotal role of the C-terminal DW-motif in mediating inhibition of pyruvate dehydrogenase kinase 2 by dichloroacetate.

Li J, Kato M, Chuang DT. Li J, et al. J Biol Chem. 2009 Dec 4;284(49):34458-67. doi: 10.1074/jbc.M109.065557. Epub 2009 Oct 15. J Biol Chem. 2009. PMID: 19833728 Free PMC article.

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