Nakagaki T - Search Results

1

Preparation of recombinant alpha-thrombin: high-level expression of recombinant human prethrombin-2 and its activation by recombinant ecarin.

Yonemura H, Imamura T, Soejima K, Nakahara Y, Morikawa W, Ushio Y, Kamachi Y, Nakatake H, Sugawara K, Nakagaki T, Nozaki C. Yonemura H, et al. Among authors: nakagaki t. J Biochem. 2004 May;135(5):577-82. doi: 10.1093/jb/mvh070. J Biochem. 2004. PMID: 15173195 Free article.

2

Analysis on the molecular species and concentration of circulating ADAMTS13 in Blood.

Soejima K, Nakamura H, Hirashima M, Morikawa W, Nozaki C, Nakagaki T. Soejima K, et al. Among authors: nakagaki t. J Biochem. 2006 Jan;139(1):147-54. doi: 10.1093/jb/mvj013. J Biochem. 2006. PMID: 16428330

3

A novel human metalloprotease synthesized in the liver and secreted into the blood: possibly, the von Willebrand factor-cleaving protease?

Soejima K, Mimura N, Hirashima M, Maeda H, Hamamoto T, Nakagaki T, Nozaki C. Soejima K, et al. Among authors: nakagaki t. J Biochem. 2001 Oct;130(4):475-80. doi: 10.1093/oxfordjournals.jbchem.a003009. J Biochem. 2001. PMID: 11574066 Free article.

4

Interplay between ADAMTS13 and von Willebrand factor in inherited and acquired thrombotic microangiopathies.

Soejima K, Nakagaki T. Soejima K, et al. Among authors: nakagaki t. Semin Hematol. 2005 Jan;42(1):56-62. doi: 10.1053/j.seminhematol.2004.09.008. Semin Hematol. 2005. PMID: 15662617 Review.

5

ADAMTS-13 cysteine-rich/spacer domains are functionally essential for von Willebrand factor cleavage.

Soejima K, Matsumoto M, Kokame K, Yagi H, Ishizashi H, Maeda H, Nozaki C, Miyata T, Fujimura Y, Nakagaki T. Soejima K, et al. Among authors: nakagaki t. Blood. 2003 Nov 1;102(9):3232-7. doi: 10.1182/blood-2003-03-0908. Epub 2003 Jul 17. Blood. 2003. PMID: 12869506 Free article.

6

The 99 and 170 loop-modified factor VIIa mutants show enhanced catalytic activity without tissue factor.

Soejima K, Yuguchi M, Mizuguchi J, Tomokiyo K, Nakashima T, Nakagaki T, Iwanaga S. Soejima K, et al. Among authors: nakagaki t. J Biol Chem. 2002 Dec 13;277(50):49027-35. doi: 10.1074/jbc.M203091200. Epub 2002 Oct 2. J Biol Chem. 2002. PMID: 12364340 Free article.

In our previous paper (Soejima, K., Mizuguchi, J., Yuguchi, M., Nakagaki, T., Higashi, S., and Iwanaga, S. (2001) J. Biol. Chem. 276, 17229-17235), the replacement of the 170 loop of VIIa with that of trypsin induced a 10-fold enhancement of the k(cat) value for S-2 …

In our previous paper (Soejima, K., Mizuguchi, J., Yuguchi, M., Nakagaki, T., Higashi, S., and Iwanaga, S. (2001) J. Biol. Che …

7

Factor VIIa modified in the 170 loop shows enhanced catalytic activity but does not change the zymogen-like property.

Soejima K, Mizuguchi J, Yuguchi M, Nakagaki T, Higashi S, Iwanaga S. Soejima K, et al. Among authors: nakagaki t. J Biol Chem. 2001 May 18;276(20):17229-35. doi: 10.1074/jbc.M009206200. Epub 2001 Feb 2. J Biol Chem. 2001. PMID: 11278475 Free article.

8

Induction of acquired factor IX inhibitors in cynomolgus monkey (Macaca fascicularis): a new primate model of hemophilia B.

Tomokiyo K, Teshima K, Nakatomi Y, Watanabe T, Mizuguchi J, Nozaki C, Nakagaki T, Miyamoto S, Funatsu A, Iwanaga S. Tomokiyo K, et al. Among authors: nakagaki t. Thromb Res. 2001 May 15;102(4):363-74. doi: 10.1016/s0049-3848(01)00253-5. Thromb Res. 2001. PMID: 11369429

9

A kinetic analysis of the interaction of human recombinant tissue factor pathway inhibitor with factor Xa utilizing and immunoassay and the effect of antithrombin III/heparin on the complex formation.

Kamikubo Y, Hamuro T, Takemoto S, Nakahara Y, Kamei S, Nakagaki T, Miyamoto S, Funatsu A, Kato H. Kamikubo Y, et al. Among authors: nakagaki t. Thromb Res. 1998 Feb 15;89(4):179-86. doi: 10.1016/s0049-3848(98)00003-6. Thromb Res. 1998. PMID: 9651145

10

Stable complex formation between serine protease inhibitor and zymogen: coagulation factor X cleaves the Arg393-Ser394 bond in a reactive centre loop of antithrombin in the presence of heparin.

Nakatomi Y, Tsuji M, Gokudan S, Hanada-Dateki T, Nakashima T, Miyazaki H, Hamamoto T, Nakagaki T, Tomokiyo K. Nakatomi Y, et al. Among authors: nakagaki t. J Biochem. 2012 Nov;152(5):463-70. doi: 10.1093/jb/mvs094. Epub 2012 Aug 24. J Biochem. 2012. PMID: 22923734

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