Wang Y - Search Results

1

Novel and potent transforming growth factor beta type I receptor kinase domain inhibitor: 7-amino 4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-quinolines.

Li HY, Wang Y, Yan L, Campbell RM, Anderson BD, Wagner JR, Yingling JM. Li HY, et al. Among authors: wang y. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3585-8. doi: 10.1016/j.bmcl.2004.04.065. Bioorg Med Chem Lett. 2004. PMID: 15177480

2

Dihydropyrrolopyrazole transforming growth factor-beta type I receptor kinase domain inhibitors: a novel benzimidazole series with selectivity versus transforming growth factor-beta type II receptor kinase and mixed lineage kinase-7.

Li HY, Wang Y, Heap CR, King CH, Mundla SR, Voss M, Clawson DK, Yan L, Campbell RM, Anderson BD, Wagner JR, Britt K, Lu KX, McMillen WT, Yingling JM. Li HY, et al. Among authors: wang y. J Med Chem. 2006 Mar 23;49(6):2138-42. doi: 10.1021/jm058209g. J Med Chem. 2006. PMID: 16539403

3

Optimization of a dihydropyrrolopyrazole series of transforming growth factor-beta type I receptor kinase domain inhibitors: discovery of an orally bioavailable transforming growth factor-beta receptor type I inhibitor as antitumor agent.

Li HY, McMillen WT, Heap CR, McCann DJ, Yan L, Campbell RM, Mundla SR, King CH, Dierks EA, Anderson BD, Britt KS, Huss KL, Voss MD, Wang Y, Clawson DK, Yingling JM, Sawyer JS. Li HY, et al. Among authors: wang y. J Med Chem. 2008 Apr 10;51(7):2302-6. doi: 10.1021/jm701199p. Epub 2008 Mar 4. J Med Chem. 2008. PMID: 18314943

4

Design and synthesis of 4-(2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-7-yl)-N-(5-(piperazin-1-ylmethyl)pyridine-2-yl)pyrimidin-2-amine as a highly potent and selective cyclin-dependent kinases 4 and 6 inhibitors and the discovery of structure-activity relationships.

Wang Y, Liu WJ, Yin L, Li H, Chen ZH, Zhu DX, Song XQ, Cheng ZZ, Song P, Wang Z, Li ZG. Wang Y, et al. Among authors: wang z. Bioorg Med Chem Lett. 2018 Mar 1;28(5):974-978. doi: 10.1016/j.bmcl.2017.12.068. Epub 2018 Jan 31. Bioorg Med Chem Lett. 2018. PMID: 29429832

5

1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors.

Zhan P, Liu X, Cao Y, Wang Y, Pannecouque C, De Clercq E. Zhan P, et al. Among authors: wang y. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5368-71. doi: 10.1016/j.bmcl.2008.09.055. Epub 2008 Sep 18. Bioorg Med Chem Lett. 2008. PMID: 18824350

6

Further studies on ethenyl and ethynyl-4-phenylamino-3-quinolinecarbonitriles: identification of a subnanomolar Src kinase inhibitor.

Barrios Sosa AC, Boschelli DH, Wu B, Wang Y, Golas JM. Barrios Sosa AC, et al. Among authors: wang y. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1743-7. doi: 10.1016/j.bmcl.2005.01.004. Bioorg Med Chem Lett. 2005. PMID: 15745832

7

First generation 5-vinyl-3-pyridinecarbonitrile PKCtheta inhibitors.

Niu C, Boschelli DH, Tumey LN, Bhagirath N, Subrath J, Shim J, Wang Y, Wu B, Eid C, Lee J, Yang X, Brennan A, Chaudhary D. Niu C, et al. Among authors: wang y. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5829-32. doi: 10.1016/j.bmcl.2009.08.086. Epub 2009 Aug 29. Bioorg Med Chem Lett. 2009. PMID: 19762237

8

Synthesis and Src kinase inhibitory activity of a series of 4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-furyl-3-quinolinecarbonitriles.

Boschelli DH, Wu B, Ye F, Wang Y, Golas JM, Lucas J, Boschelli F. Boschelli DH, et al. Among authors: wang y. J Med Chem. 2006 Dec 28;49(26):7868-76. doi: 10.1021/jm061031t. J Med Chem. 2006. PMID: 17181170

9

Optimization of 7-alkene-3-quinolinecarbonitriles as Src kinase inhibitors.

Boschelli DH, Wang D, Wang Y, Wu B, Honores EE, Barrios Sosa AC, Chaudhary I, Golas J, Lucas J, Boschelli F. Boschelli DH, et al. Among authors: wang y, wang d. Bioorg Med Chem Lett. 2010 May 1;20(9):2924-7. doi: 10.1016/j.bmcl.2010.03.025. Epub 2010 Mar 7. Bioorg Med Chem Lett. 2010. PMID: 20363128

10

Discovery of novel imidazo[1,2-a]pyrazin-8-amines as Brk/PTK6 inhibitors.

Zeng H, Belanger DB, Curran PJ, Shipps GW Jr, Miao H, Bracken JB, Arshad Siddiqui M, Malkowski M, Wang Y. Zeng H, et al. Among authors: wang y. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5870-5. doi: 10.1016/j.bmcl.2011.07.101. Epub 2011 Aug 3. Bioorg Med Chem Lett. 2011. PMID: 21855335

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