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Direct orthotopic transplantation of fresh surgical specimen preserves CD133+ tumor cells in clinically relevant mouse models of medulloblastoma and glioma.
Shu Q, Wong KK, Su JM, Adesina AM, Yu LT, Tsang YT, Antalffy BC, Baxter P, Perlaky L, Yang J, Dauser RC, Chintagumpala M, Blaney SM, Lau CC, Li XN. Shu Q, et al. Among authors: li xn. Stem Cells. 2008 Jun;26(6):1414-24. doi: 10.1634/stemcells.2007-1009. Epub 2008 Apr 10. Stem Cells. 2008. PMID: 18403755
A clinically relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivo.
Yu L, Baxter PA, Voicu H, Gurusiddappa S, Zhao Y, Adesina A, Man TK, Shu Q, Zhang YJ, Zhao XM, Su JM, Perlaky L, Dauser R, Chintagumpala M, Lau CC, Blaney SM, Rao PH, Leung HC, Li XN. Yu L, et al. Among authors: li xn. Neuro Oncol. 2010 Jun;12(6):580-94. doi: 10.1093/neuonc/nop056. Epub 2010 Feb 8. Neuro Oncol. 2010. PMID: 20511191 Free PMC article.
Crosstalk between medulloblastoma cells and endothelium triggers a strong chemotactic signal recruiting T lymphocytes to the tumor microenvironment.
Salsman VS, Chow KK, Shaffer DR, Kadikoy H, Li XN, Gerken C, Perlaky L, Metelitsa LS, Gao X, Bhattacharjee M, Hirschi K, Heslop HE, Gottschalk S, Ahmed N. Salsman VS, et al. Among authors: li xn. PLoS One. 2011;6(5):e20267. doi: 10.1371/journal.pone.0020267. Epub 2011 May 27. PLoS One. 2011. PMID: 21647415 Free PMC article.
1,054 results