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p38alpha stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis.
Ackerley S, Grierson AJ, Banner S, Perkinton MS, Brownlees J, Byers HL, Ward M, Thornhill P, Hussain K, Waby JS, Anderton BH, Cooper JD, Dingwall C, Leigh PN, Shaw CE, Miller CC. Ackerley S, et al. Among authors: dingwall c. Mol Cell Neurosci. 2004 Jun;26(2):354-64. doi: 10.1016/j.mcn.2004.02.009. Mol Cell Neurosci. 2004. PMID: 15207859
ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site.
Hussain I, Powell DJ, Howlett DR, Chapman GA, Gilmour L, Murdock PR, Tew DG, Meek TD, Chapman C, Schneider K, Ratcliffe SJ, Tattersall D, Testa TT, Southan C, Ryan DM, Simmons DL, Walsh FS, Dingwall C, Christie G. Hussain I, et al. Among authors: dingwall c. Mol Cell Neurosci. 2000 Nov;16(5):609-19. doi: 10.1006/mcne.2000.0884. Mol Cell Neurosci. 2000. PMID: 11083922
Identification of a novel aspartic protease (Asp 2) as beta-secretase.
Hussain I, Powell D, Howlett DR, Tew DG, Meek TD, Chapman C, Gloger IS, Murphy KE, Southan CD, Ryan DM, Smith TS, Simmons DL, Walsh FS, Dingwall C, Christie G. Hussain I, et al. Among authors: dingwall c. Mol Cell Neurosci. 1999 Dec;14(6):419-27. doi: 10.1006/mcne.1999.0811. Mol Cell Neurosci. 1999. PMID: 10656250
94 results