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The consequences of reducing expression of the alpha7 nicotinic receptor by RNA interference and of stimulating its activity with an alpha7 agonist in SH-SY5Y cells indicate that this receptor plays a neuroprotective role in connection with the pathogenesis of Alzheimer's disease.
Qi XL, Nordberg A, Xiu J, Guan ZZ. Qi XL, et al. Among authors: nordberg a. Neurochem Int. 2007 Nov-Dec;51(6-7):377-83. doi: 10.1016/j.neuint.2007.04.002. Epub 2007 Apr 8. Neurochem Int. 2007. PMID: 17493709
541 results