Spelsberg TC - Search Results

1

Differential gene expression of TGF beta inducible early gene (TIEG), Smad7, Smad2 and Bard1 in normal and malignant breast tissue.

Reinholz MM, An MW, Johnsen SA, Subramaniam M, Suman VJ, Ingle JN, Roche PC, Spelsberg TC. Reinholz MM, et al. Among authors: spelsberg tc. Breast Cancer Res Treat. 2004 Jul;86(1):75-88. doi: 10.1023/B:BREA.0000032926.74216.7d. Breast Cancer Res Treat. 2004. PMID: 15218362

2

Transcriptional regulation of Smad2 is required for enhancement of TGFbeta/Smad signaling by TGFbeta inducible early gene.

Johnsen SA, Subramaniam M, Katagiri T, Janknecht R, Spelsberg TC. Johnsen SA, et al. Among authors: spelsberg tc. J Cell Biochem. 2002;87(2):233-41. doi: 10.1002/jcb.10299. J Cell Biochem. 2002. PMID: 12244575

3

Overexpression of the TGF-beta antagonist Smad7 in endometrial cancer.

Dowdy SC, Mariani A, Reinholz MM, Keeney GL, Spelsberg TC, Podratz KC, Janknecht R. Dowdy SC, et al. Among authors: spelsberg tc. Gynecol Oncol. 2005 Feb;96(2):368-73. doi: 10.1016/j.ygyno.2004.10.006. Gynecol Oncol. 2005. PMID: 15661223

4

The tamoxifen metabolite, endoxifen, is a potent antiestrogen that targets estrogen receptor alpha for degradation in breast cancer cells.

Wu X, Hawse JR, Subramaniam M, Goetz MP, Ingle JN, Spelsberg TC. Wu X, et al. Among authors: spelsberg tc. Cancer Res. 2009 Mar 1;69(5):1722-7. doi: 10.1158/0008-5472.CAN-08-3933. Epub 2009 Feb 24. Cancer Res. 2009. PMID: 19244106

5

Estrogen receptor-beta sensitizes breast cancer cells to the anti-estrogenic actions of endoxifen.

Wu X, Subramaniam M, Grygo SB, Sun Z, Negron V, Lingle WL, Goetz MP, Ingle JN, Spelsberg TC, Hawse JR. Wu X, et al. Among authors: spelsberg tc. Breast Cancer Res. 2011 Mar 10;13(2):R27. doi: 10.1186/bcr2844. Breast Cancer Res. 2011. PMID: 21392396 Free PMC article.

6

TGFβ inducible early gene-1 plays an important role in mediating estrogen signaling in the skeleton.

Hawse JR, Pitel KS, Cicek M, Philbrick KA, Gingery A, Peters KD, Syed FA, Ingle JN, Suman VJ, Iwaniec UT, Turner RT, Spelsberg TC, Subramaniam M. Hawse JR, et al. Among authors: spelsberg tc. J Bone Miner Res. 2014;29(5):1206-16. doi: 10.1002/jbmr.2142. J Bone Miner Res. 2014. PMID: 24190163 Free PMC article.

7

Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGFbeta-inducible early gene-1 by human seven in absentia homologue.

Johnsen SA, Subramaniam M, Monroe DG, Janknecht R, Spelsberg TC. Johnsen SA, et al. Among authors: spelsberg tc. J Biol Chem. 2002 Aug 23;277(34):30754-9. doi: 10.1074/jbc.M204812200. Epub 2002 Jun 18. J Biol Chem. 2002. PMID: 12072443 Free article.

8

TGFbeta inducible early gene enhances TGFbeta/Smad-dependent transcriptional responses.

Johnsen SA, Subramaniam M, Janknecht R, Spelsberg TC. Johnsen SA, et al. Among authors: spelsberg tc. Oncogene. 2002 Aug 22;21(37):5783-90. doi: 10.1038/sj.onc.1205681. Oncogene. 2002. PMID: 12173049

9

Tissue, cell type, and breast cancer stage-specific expression of a TGF-beta inducible early transcription factor gene.

Subramaniam M, Hefferan TE, Tau K, Peus D, Pittelkow M, Jalal S, Riggs BL, Roche P, Spelsberg TC. Subramaniam M, et al. Among authors: spelsberg tc. J Cell Biochem. 1998 Feb 1;68(2):226-36. J Cell Biochem. 1998. PMID: 9443078

10

Overexpression of a nuclear protein, TIEG, mimics transforming growth factor-beta action in human osteoblast cells.

Hefferan TE, Reinholz GG, Rickard DJ, Johnsen SA, Waters KM, Subramaniam M, Spelsberg TC. Hefferan TE, et al. Among authors: spelsberg tc. J Biol Chem. 2000 Jul 7;275(27):20255-9. doi: 10.1074/jbc.C000135200. J Biol Chem. 2000. PMID: 10816551 Free article.

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