Bohlen P - Search Results

1

Inhibition of both the autocrine and the paracrine growth of human leukemia with a fully human antibody directed against vascular endothelial growth factor receptor 2.

Zhang H, Li Y, Li H, Bassi R, Jimenez X, Witte L, Bohlen P, Hicklin D, Zhu Z. Zhang H, et al. Among authors: bohlen p. Leuk Lymphoma. 2004 Sep;45(9):1887-97. doi: 10.1080/10428190410001712225. Leuk Lymphoma. 2004. PMID: 15223651

2

Selection of high affinity human neutralizing antibodies to VEGFR2 from a large antibody phage display library for antiangiogenesis therapy.

Lu D, Jimenez X, Zhang H, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: bohlen p. Int J Cancer. 2002 Jan 20;97(3):393-9. doi: 10.1002/ijc.1634. Int J Cancer. 2002. PMID: 11774295

3

Active immunization against the vascular endothelial growth factor receptor flk1 inhibits tumor angiogenesis and metastasis.

Li Y, Wang MN, Li H, King KD, Bassi R, Sun H, Santiago A, Hooper AT, Bohlen P, Hicklin DJ. Li Y, et al. Among authors: bohlen p. J Exp Med. 2002 Jun 17;195(12):1575-84. doi: 10.1084/jem.20020072. J Exp Med. 2002. PMID: 12070285 Free PMC article.

4

Fab-scFv fusion protein: an efficient approach to production of bispecific antibody fragments.

Lu D, Jimenez X, Zhang H, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: bohlen p. J Immunol Methods. 2002 Sep 15;267(2):213-26. doi: 10.1016/s0022-1759(02)00148-5. J Immunol Methods. 2002. PMID: 12165442

5

Clinical development of angiogenesis inhibitors to vascular endothelial growth factor and its receptors as cancer therapeutics.

Zhu Z, Bohlen P, Witte L. Zhu Z, et al. Among authors: bohlen p. Curr Cancer Drug Targets. 2002 Jun;2(2):135-56. doi: 10.2174/1568009023333881. Curr Cancer Drug Targets. 2002. PMID: 12188915 Review.

6

Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity.

Lu D, Shen J, Vil MD, Zhang H, Jimenez X, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: bohlen p. J Biol Chem. 2003 Oct 31;278(44):43496-507. doi: 10.1074/jbc.M307742200. Epub 2003 Aug 12. J Biol Chem. 2003. PMID: 12917408 Free article.

7

Di-diabody: a novel tetravalent bispecific antibody molecule by design.

Lu D, Jimenez X, Zhang H, Atkins A, Brennan L, Balderes P, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: bohlen p. J Immunol Methods. 2003 Aug;279(1-2):219-32. doi: 10.1016/s0022-1759(03)00251-5. J Immunol Methods. 2003. PMID: 12969563

8

Simultaneous blockade of both the epidermal growth factor receptor and the insulin-like growth factor receptor signaling pathways in cancer cells with a fully human recombinant bispecific antibody.

Lu D, Zhang H, Ludwig D, Persaud A, Jimenez X, Burtrum D, Balderes P, Liu M, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: bohlen p. J Biol Chem. 2004 Jan 23;279(4):2856-65. doi: 10.1074/jbc.M310132200. Epub 2003 Oct 23. J Biol Chem. 2004. PMID: 14576153 Free article.

9

A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.

Burtrum D, Zhu Z, Lu D, Anderson DM, Prewett M, Pereira DS, Bassi R, Abdullah R, Hooper AT, Koo H, Jimenez X, Johnson D, Apblett R, Kussie P, Bohlen P, Witte L, Hicklin DJ, Ludwig DL. Burtrum D, et al. Among authors: bohlen p. Cancer Res. 2003 Dec 15;63(24):8912-21. Cancer Res. 2003. PMID: 14695208

10

Suppression of leukemia expressing wild-type or ITD-mutant FLT3 receptor by a fully human anti-FLT3 neutralizing antibody.

Li Y, Li H, Wang MN, Lu D, Bassi R, Wu Y, Zhang H, Balderes P, Ludwig DL, Pytowski B, Kussie P, Piloto O, Small D, Bohlen P, Witte L, Zhu Z, Hicklin DJ. Li Y, et al. Among authors: bohlen p. Blood. 2004 Aug 15;104(4):1137-44. doi: 10.1182/blood-2003-07-2585. Epub 2004 Apr 22. Blood. 2004. PMID: 15105287 Free article.

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