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583 results

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Page 1
Novel potent 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities.
Cappelli A, Anzini M, Vomero S, Mennuni L, Makovec F, Doucet E, Hamon M, Menziani MC, De Benedetti PG, Giorgi G, Ghelardini C, Collina S. Cappelli A, et al. Among authors: giorgi g. Bioorg Med Chem. 2002 Mar;10(3):779-801. doi: 10.1016/s0968-0896(01)00332-7. Bioorg Med Chem. 2002. PMID: 11814868
Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure.
Cappelli A, Pericot Mohr Gl Gl, Gallelli A, Rizzo M, Anzini M, Vomero S, Mennuni L, Ferrari F, Makovec F, Menziani MC, De Benedetti PG, Giorgi G. Cappelli A, et al. Among authors: giorgi g. J Med Chem. 2004 May 6;47(10):2574-86. doi: 10.1021/jm031100t. J Med Chem. 2004. PMID: 15115399
Physicochemical and biopharmaceutical characterization of endo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1H-benz[e]isoindol-1-one (CR3124) a novel potent 5-HT3 receptor antagonist.
Cappelli A, Travagli V, Zanardi I, Anzini M, Giorgi G, Donati A, Aggravi M, Casolaro M, Fresta M, Paccagnini E, Makovec F, Vomero S. Cappelli A, et al. Among authors: giorgi g. J Pharm Sci. 2006 Dec;95(12):2706-21. doi: 10.1002/jps.20705. J Pharm Sci. 2006. PMID: 16924684
Further studies on imidazo[4,5-b]pyridine AT1 angiotensin II receptor antagonists. Effects of the transformation of the 4-phenylquinoline backbone into 4-phenylisoquinolinone or 1-phenylindene scaffolds.
Cappelli A, Pericot Mohr Gl, Giuliani G, Galeazzi S, Anzini M, Mennuni L, Ferrari F, Makovec F, Kleinrath EM, Langer T, Valoti M, Giorgi G, Vomero S. Cappelli A, et al. Among authors: giorgi g. J Med Chem. 2006 Nov 2;49(22):6451-64. doi: 10.1021/jm0603163. J Med Chem. 2006. PMID: 17064065
Design, synthesis, and biological evaluation of AT1 angiotensin II receptor antagonists based on the pyrazolo[3,4-b]pyridine and related heteroaromatic bicyclic systems.
Cappelli A, Nannicini C, Gallelli A, Giuliani G, Valenti S, Mohr Gl, Anzini M, Mennuni L, Ferrari F, Caselli G, Giordani A, Peris W, Makovec F, Giorgi G, Vomero S. Cappelli A, et al. Among authors: giorgi g. J Med Chem. 2008 Apr 10;51(7):2137-46. doi: 10.1021/jm7011563. Epub 2008 Mar 5. J Med Chem. 2008. PMID: 18318468
583 results