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1,7-annulated indolocarbazoles as cyclin-dependent kinase inhibitors.
Al-awar RS, Ray JE, Hecker KA, Huang J, Waid PP, Shih C, Brooks HB, Spencer CD, Watkins SA, Patel BR, Stamm NB, Ogg CA, Schultz RM, Considine EL, Faul MM, Sullivan KA, Kolis SP, Grutsch JL, Joseph S. Al-awar RS, et al. Among authors: joseph s. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3217-20. doi: 10.1016/j.bmcl.2004.03.105. Bioorg Med Chem Lett. 2004. PMID: 15149678
Anthranilamide inhibitors of factor Xa.
Mendel D, Marquart AL, Joseph S, Waid P, Yee YK, Tebbe AL, Ratz AM, Herron DK, Goodson T, Masters JJ, Franciskovich JB, Tinsley JM, Wiley MR, Weir LC, Kyle JA, Klimkowski VJ, Smith GF, Towner RD, Froelich LL, Buben J, Craft TJ. Mendel D, et al. Among authors: joseph s. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4832-6. doi: 10.1016/j.bmcl.2007.06.051. Epub 2007 Jun 20. Bioorg Med Chem Lett. 2007. PMID: 17624775
A phase I trial of LY2584702 tosylate, a p70 S6 kinase inhibitor, in patients with advanced solid tumours.
Tolcher A, Goldman J, Patnaik A, Papadopoulos KP, Westwood P, Kelly CS, Bumgardner W, Sams L, Geeganage S, Wang T, Capen AR, Huang J, Joseph S, Miller J, Benhadji KA, Brail LH, Rosen LS. Tolcher A, et al. Among authors: joseph s. Eur J Cancer. 2014 Mar;50(5):867-75. doi: 10.1016/j.ejca.2013.11.039. Epub 2014 Jan 15. Eur J Cancer. 2014. PMID: 24440085 Clinical Trial.
ERK Inhibitor LY3214996 Targets ERK Pathway-Driven Cancers: A Therapeutic Approach Toward Precision Medicine.
Bhagwat SV, McMillen WT, Cai S, Zhao B, Whitesell M, Shen W, Kindler L, Flack RS, Wu W, Anderson B, Zhai Y, Yuan XJ, Pogue M, Van Horn RD, Rao X, McCann D, Dropsey AJ, Manro J, Walgren J, Yuen E, Rodriguez MJ, Plowman GD, Tiu RV, Joseph S, Peng SB. Bhagwat SV, et al. Among authors: joseph s. Mol Cancer Ther. 2020 Feb;19(2):325-336. doi: 10.1158/1535-7163.MCT-19-0183. Epub 2019 Nov 19. Mol Cancer Ther. 2020. PMID: 31744895
The persistent pool of HIV-1-infected cells is formed episodically during untreated infection.
Council OD, Tyers L, Moeser M, Sondgeroth A, Spielvogel E, Richardson BD, Doolabh D, Zhou S, Emery A, Archin NM, Shook-Sa B, Margolis DM, Abdool Karim SS, Kosakovsky Pond S, Garrett N, Abrahams M-R, Joseph SB, Williamson C, Swanstrom R. Council OD, et al. Among authors: joseph sb. J Virol. 2024 Dec 26:e0097924. doi: 10.1128/jvi.00979-24. Online ahead of print. J Virol. 2024. PMID: 39723838
2,453 results