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Alpha4beta1 integrin affinity changes govern cell adhesion.
Chigaev A, Zwartz G, Graves SW, Dwyer DC, Tsuji H, Foutz TD, Edwards BS, Prossnitz ER, Larson RS, Sklar LA. Chigaev A, et al. J Biol Chem. 2003 Oct 3;278(40):38174-82. doi: 10.1074/jbc.M210472200. Epub 2003 Jul 3. J Biol Chem. 2003. PMID: 12844491 Free article.
Different mechanisms, including changes in the number of interacting molecules due to the alteration of the receptor topology or changes in the affinity of the individual bonds, have been proposed to explain the nature of these fast changes in avidity. Recently, we described a …
Different mechanisms, including changes in the number of interacting molecules due to the alteration of the receptor topology or changes in …
Conformational regulation of alpha 4 beta 1-integrin affinity by reducing agents. "Inside-out" signaling is independent of and additive to reduction-regulated integrin activation.
Chigaev A, Zwartz GJ, Buranda T, Edwards BS, Prossnitz ER, Sklar LA. Chigaev A, et al. J Biol Chem. 2004 Jul 30;279(31):32435-43. doi: 10.1074/jbc.M404387200. Epub 2004 May 27. J Biol Chem. 2004. PMID: 15166232 Free article.
Recently, we described a fluorescent LDV-containing small molecule that was used to monitor VLA-4 affinity changes in live cells (Chigaev, A., Blenc, A. ...S., Prossnitz, E. R., Larson, R. S., and Sklar, L. A. (2001) J. Biol. Chem. 276, 48670-48 …
Recently, we described a fluorescent LDV-containing small molecule that was used to monitor VLA-4 affinity changes in live cells ( …
47 results