Gearhart PJ - Search Results

1

A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination.

Martomo SA, Yang WW, Gearhart PJ. Martomo SA, et al. Among authors: gearhart pj. J Exp Med. 2004 Jul 5;200(1):61-8. doi: 10.1084/jem.20040691. J Exp Med. 2004. PMID: 15238605 Free PMC article.

2

Absence of DNA polymerase eta reveals targeting of C mutations on the nontranscribed strand in immunoglobulin switch regions.

Zeng X, Negrete GA, Kasmer C, Yang WW, Gearhart PJ. Zeng X, et al. Among authors: gearhart pj. J Exp Med. 2004 Apr 5;199(7):917-24. doi: 10.1084/jem.20032022. Epub 2004 Mar 29. J Exp Med. 2004. PMID: 15051760 Free PMC article.

3

MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes.

Wilson TM, Vaisman A, Martomo SA, Sullivan P, Lan L, Hanaoka F, Yasui A, Woodgate R, Gearhart PJ. Wilson TM, et al. Among authors: gearhart pj. J Exp Med. 2005 Feb 21;201(4):637-45. doi: 10.1084/jem.20042066. Epub 2005 Feb 14. J Exp Med. 2005. PMID: 15710654 Free PMC article.

4

Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification.

Martomo SA, Yang WW, Wersto RP, Ohkumo T, Kondo Y, Yokoi M, Masutani C, Hanaoka F, Gearhart PJ. Martomo SA, et al. Among authors: gearhart pj. Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8656-61. doi: 10.1073/pnas.0501852102. Epub 2005 Jun 6. Proc Natl Acad Sci U S A. 2005. PMID: 15939880 Free PMC article.

5

Deoxyuridine is generated preferentially in the nontranscribed strand of DNA from cells expressing activation-induced cytidine deaminase.

Martomo SA, Fu D, Yang WW, Joshi NS, Gearhart PJ. Martomo SA, et al. Among authors: gearhart pj. J Immunol. 2005 Jun 15;174(12):7787-91. doi: 10.4049/jimmunol.174.12.7787. J Immunol. 2005. PMID: 15944282

6

Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota.

Martomo SA, Yang WW, Vaisman A, Maas A, Yokoi M, Hoeijmakers JH, Hanaoka F, Woodgate R, Gearhart PJ. Martomo SA, et al. Among authors: gearhart pj. DNA Repair (Amst). 2006 Mar 7;5(3):392-8. doi: 10.1016/j.dnarep.2005.12.006. Epub 2006 Jan 26. DNA Repair (Amst). 2006. PMID: 16443401

7

Somatic hypermutation: subverted DNA repair.

Martomo SA, Gearhart PJ. Martomo SA, et al. Among authors: gearhart pj. Curr Opin Immunol. 2006 Jun;18(3):243-8. doi: 10.1016/j.coi.2006.03.007. Epub 2006 Apr 17. Curr Opin Immunol. 2006. PMID: 16616477 Review.

8

Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes.

Martomo SA, Saribasak H, Yokoi M, Hanaoka F, Gearhart PJ. Martomo SA, et al. Among authors: gearhart pj. DNA Repair (Amst). 2008 Sep 1;7(9):1603-8. doi: 10.1016/j.dnarep.2008.04.002. Epub 2008 May 16. DNA Repair (Amst). 2008. PMID: 18485835 Free PMC article.

9

Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions.

Maul RW, Saribasak H, Martomo SA, McClure RL, Yang W, Vaisman A, Gramlich HS, Schatz DG, Woodgate R, Wilson DM 3rd, Gearhart PJ. Maul RW, et al. Among authors: gearhart pj. Nat Immunol. 2011 Jan;12(1):70-6. doi: 10.1038/ni.1970. Epub 2010 Dec 12. Nat Immunol. 2011. PMID: 21151102 Free PMC article.

10

XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in Igh genes.

Saribasak H, Maul RW, Cao Z, McClure RL, Yang W, McNeill DR, Wilson DM 3rd, Gearhart PJ. Saribasak H, et al. Among authors: gearhart pj. J Exp Med. 2011 Oct 24;208(11):2209-16. doi: 10.1084/jem.20111135. Epub 2011 Oct 3. J Exp Med. 2011. PMID: 21967769 Free PMC article.

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