Ciobanu LC - Search Results

1

Maltais R, Tremblay MR, Ciobanu LC, Poirier D. Maltais R, et al. Among authors: ciobanu lc. J Comb Chem. 2004 Jul-Aug;6(4):443-56. doi: 10.1021/cc030118m. J Comb Chem. 2004. PMID: 15244402 Review. No abstract available.

2

Solid-phase parallel synthesis of 17alpha-substituted estradiol sulfamate and phenol libraries using the multidetachable sulfamate linker.

Ciobanu LC, Poirier D. Ciobanu LC, et al. J Comb Chem. 2003 Jul-Aug;5(4):429-40. doi: 10.1021/cc020115u. J Comb Chem. 2003. PMID: 12857111

3

A multidetachable sulfamate linker successfully used in a solid-phase strategy to generate libraries of sulfamate and phenol derivatives.

Poirier D, Ciobanu LC, Bérubé M. Poirier D, et al. Among authors: ciobanu lc. Bioorg Med Chem Lett. 2002 Oct 21;12(20):2833-8. doi: 10.1016/s0960-894x(02)00637-6. Bioorg Med Chem Lett. 2002. PMID: 12270157

4

3Beta-sulfamate derivatives of C19 and C21 steroids bearing a t-butylbenzyl or a benzyl group: synthesis and evaluation as non-estrogenic and non-androgenic steroid sulfatase inhibitors.

Ciobanu LC, Boivin RP, Luu-The V, Poirier D. Ciobanu LC, et al. J Enzyme Inhib Med Chem. 2003 Feb;18(1):15-26. doi: 10.1080/1475636031000069282. J Enzyme Inhib Med Chem. 2003. PMID: 12751816 Free article.

5

Synthesis of libraries of 16beta-aminopropyl estradiol derivatives for targeting two key steroidogenic enzymes.

Ciobanu LC, Poirier D. Ciobanu LC, et al. ChemMedChem. 2006 Nov;1(11):1249-59. doi: 10.1002/cmdc.200600071. ChemMedChem. 2006. PMID: 16986200

6

Nonsteroidal compounds designed to mimic potent steroid sulfatase inhibitors.

Ciobanu LC, Luu-The V, Poirier D. Ciobanu LC, et al. J Steroid Biochem Mol Biol. 2002 Mar;80(3):339-53. doi: 10.1016/s0960-0760(02)00024-9. J Steroid Biochem Mol Biol. 2002. PMID: 11948019

7

Synthesis and steroid sulphatase inhibitory activity of C19- and C21-steroidal derivatives bearing a benzyl-inhibiting group.

Ciobanu LC, Boivin RP, Luu-The V, Poirier D. Ciobanu LC, et al. Eur J Med Chem. 2001 Jul-Aug;36(7-8):659-71. doi: 10.1016/s0223-5234(01)01262-4. Eur J Med Chem. 2001. PMID: 11600235

8

Inhibition of estrone sulfate-induced uterine growth by potent nonestrogenic steroidal inhibitors of steroid sulfatase.

Ciobanu LC, Luu-The V, Martel C, Labrie F, Poirier D. Ciobanu LC, et al. Cancer Res. 2003 Oct 1;63(19):6442-6. Cancer Res. 2003. PMID: 14559834

9

Potent inhibition of steroid sulfatase activity by 3-O-sulfamate 17alpha-benzyl(or 4'-tert-butylbenzyl)estra-1,3,5(10)-trienes: combination of two substituents at positions C3 and c17alpha of estradiol.

Ciobanu LC, Boivin RP, Luu-The V, Labrie F, Poirier D. Ciobanu LC, et al. J Med Chem. 1999 Jun 17;42(12):2280-6. doi: 10.1021/jm980677l. J Med Chem. 1999. PMID: 10377235

10

Structural characterization of the human androgen receptor ligand-binding domain complexed with EM5744, a rationally designed steroidal ligand bearing a bulky chain directed toward helix 12.

Cantin L, Faucher F, Couture JF, de Jésus-Tran KP, Legrand P, Ciobanu LC, Fréchette Y, Labrecque R, Singh SM, Labrie F, Breton R. Cantin L, et al. Among authors: ciobanu lc. J Biol Chem. 2007 Oct 19;282(42):30910-9. doi: 10.1074/jbc.M705524200. Epub 2007 Aug 21. J Biol Chem. 2007. PMID: 17711855 Free article.

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