Robakis NK - Search Results

1

The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice.

Wen PH, Hof PR, Chen X, Gluck K, Austin G, Younkin SG, Younkin LH, DeGasperi R, Gama Sosa MA, Robakis NK, Haroutunian V, Elder GA. Wen PH, et al. Among authors: robakis nk. Exp Neurol. 2004 Aug;188(2):224-37. doi: 10.1016/j.expneurol.2004.04.002. Exp Neurol. 2004. PMID: 15246822

2

Presenilin-1 is expressed in neural progenitor cells in the hippocampus of adult mice.

Wen PH, Friedrich VL Jr, Shioi J, Robakis NK, Elder GA. Wen PH, et al. Among authors: robakis nk. Neurosci Lett. 2002 Jan 25;318(2):53-6. doi: 10.1016/s0304-3940(01)02485-5. Neurosci Lett. 2002. PMID: 11796184

3

Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice.

Wen PH, Shao X, Shao Z, Hof PR, Wisniewski T, Kelley K, Friedrich VL Jr, Ho L, Pasinetti GM, Shioi J, Robakis NK, Elder GA. Wen PH, et al. Among authors: robakis nk. Neurobiol Dis. 2002 Jun;10(1):8-19. doi: 10.1006/nbdi.2002.0490. Neurobiol Dis. 2002. PMID: 12079399

4

PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations.

Baki L, Shioi J, Wen P, Shao Z, Schwarzman A, Gama-Sosa M, Neve R, Robakis NK. Baki L, et al. Among authors: robakis nk. EMBO J. 2004 Jul 7;23(13):2586-96. doi: 10.1038/sj.emboj.7600251. Epub 2004 Jun 10. EMBO J. 2004. PMID: 15192701 Free PMC article.

5

Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanisms.

Bruban J, Voloudakis G, Huang Q, Kajiwara Y, Al Rahim M, Yoon Y, Shioi J, Gama Sosa MA, Shao Z, Georgakopoulos A, Robakis NK. Bruban J, et al. Among authors: robakis nk. FASEB J. 2015 Sep;29(9):3702-12. doi: 10.1096/fj.15-270645. Epub 2015 May 18. FASEB J. 2015. PMID: 25985800 Free PMC article.

6

Phospholipid dysregulation contributes to ApoE4-associated cognitive deficits in Alzheimer's disease pathogenesis.

Zhu L, Zhong M, Elder GA, Sano M, Holtzman DM, Gandy S, Cardozo C, Haroutunian V, Robakis NK, Cai D. Zhu L, et al. Among authors: robakis nk. Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11965-70. doi: 10.1073/pnas.1510011112. Epub 2015 Sep 8. Proc Natl Acad Sci U S A. 2015. PMID: 26372964 Free PMC article.

7

Presenilin-1-immunoreactive neurons are preserved in late-onset Alzheimer's disease.

Giannakopoulos P, Bouras C, Kövari E, Shioi J, Tezapsidis N, Hof PR, Robakis NK. Giannakopoulos P, et al. Among authors: robakis nk. Am J Pathol. 1997 Feb;150(2):429-36. Am J Pathol. 1997. PMID: 9033258 Free PMC article.

8

A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations.

Marambaud P, Wen PH, Dutt A, Shioi J, Takashima A, Siman R, Robakis NK. Marambaud P, et al. Among authors: robakis nk. Cell. 2003 Sep 5;114(5):635-45. doi: 10.1016/j.cell.2003.08.008. Cell. 2003. PMID: 13678586 Free article.

9

The presenilin-1 familial Alzheimer's disease mutation P117L decreases neuronal differentiation of embryonic murine neural progenitor cells.

Eder-Colli L, Abad-Estarlich N, Pannetier C, Vallet PG, Walzer C, Elder GA, Robakis NK, Bouras C, Savioz A. Eder-Colli L, et al. Among authors: robakis nk. Brain Res Bull. 2009 Oct 28;80(4-5):296-301. doi: 10.1016/j.brainresbull.2009.06.007. Epub 2009 Jun 23. Brain Res Bull. 2009. PMID: 19555743 Free PMC article.

10

Identification and neuron specific expression of the S182/presenilin I protein in human and rodent brains.

Elder GA, Tezapsidis N, Carter J, Shioi J, Bouras C, Li HC, Johnston JM, Efthimiopoulos S, Friedrich VL Jr, Robakis NK. Elder GA, et al. Among authors: robakis nk. J Neurosci Res. 1996 Aug 1;45(3):308-20. doi: 10.1002/(SICI)1097-4547(19960801)45:3<308::AID-JNR13>3.0.CO;2-#. J Neurosci Res. 1996. PMID: 8841992

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