Trail P - Search Results

1

Monoclonal antibody mediated intracellular targeting of tallysomycin S(10b).

Walker MA, King HD, Dalterio RA, Trail P, Firestone R, Dubowchik GM. Walker MA, et al. Among authors: trail p. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4323-7. doi: 10.1016/j.bmcl.2004.05.089. Bioorg Med Chem Lett. 2004. PMID: 15261295

2

Synthesis of an immunoconjugate of camptothecin.

Walker MA, Dubowchik GM, Hofstead SJ, Trail PA, Firestone RA. Walker MA, et al. Bioorg Med Chem Lett. 2002 Jan 21;12(2):217-9. doi: 10.1016/s0960-894x(01)00707-7. Bioorg Med Chem Lett. 2002. PMID: 11755358

3

Doxorubicin immunoconjugates containing bivalent, lysosomally-cleavable dipeptide linkages.

Dubowchik GM, Radia S, Mastalerz H, Walker MA, Firestone RA, Dalton King H, Hofstead SJ, Willner D, Lasch SJ, Trail PA. Dubowchik GM, et al. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1529-32. doi: 10.1016/s0960-894x(02)00194-4. Bioorg Med Chem Lett. 2002. PMID: 12031335

4

Monoclonal antibody conjugates of doxorubicin prepared with branched peptide linkers: inhibition of aggregation by methoxytriethyleneglycol chains.

King HD, Dubowchik GM, Mastalerz H, Willner D, Hofstead SJ, Firestone RA, Lasch SJ, Trail PA. King HD, et al. J Med Chem. 2002 Sep 12;45(19):4336-43. doi: 10.1021/jm020149g. J Med Chem. 2002. PMID: 12213074

5

BR96 conjugates of highly potent anthracyclines.

King HD, Staab AJ, Pham-Kaplita K, Yurgaitis D, Firestone RA, Lasch SJ, Trail PA. King HD, et al. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2119-22. doi: 10.1016/s0960-894x(03)00375-5. Bioorg Med Chem Lett. 2003. PMID: 12798317

6

Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: model studies of enzymatic drug release and antigen-specific in vitro anticancer activity.

Dubowchik GM, Firestone RA, Padilla L, Willner D, Hofstead SJ, Mosure K, Knipe JO, Lasch SJ, Trail PA. Dubowchik GM, et al. Bioconjug Chem. 2002 Jul-Aug;13(4):855-69. doi: 10.1021/bc025536j. Bioconjug Chem. 2002. PMID: 12121142

7

Monoclonal antibody drug immunoconjugates for targeted treatment of cancer.

Trail PA, King HD, Dubowchik GM. Trail PA, et al. Cancer Immunol Immunother. 2003 May;52(5):328-37. doi: 10.1007/s00262-002-0352-9. Epub 2003 Jan 16. Cancer Immunol Immunother. 2003. PMID: 12700948 Free PMC article. Review.

8

Antibody drug conjugates for treatment of breast cancer: Novel targets and diverse approaches in ADC design.

Trail PA, Dubowchik GM, Lowinger TB. Trail PA, et al. Pharmacol Ther. 2018 Jan;181:126-142. doi: 10.1016/j.pharmthera.2017.07.013. Epub 2017 Jul 27. Pharmacol Ther. 2018. PMID: 28757155 Review.

9

(6-Maleimidocaproyl)hydrazone of doxorubicin--a new derivative for the preparation of immunoconjugates of doxorubicin.

Willner D, Trail PA, Hofstead SJ, King HD, Lasch SJ, Braslawsky GR, Greenfield RS, Kaneko T, Firestone RA. Willner D, et al. Among authors: trail pa. Bioconjug Chem. 1993 Nov-Dec;4(6):521-7. doi: 10.1021/bc00024a015. Bioconjug Chem. 1993. PMID: 7508268

10

Monoclonal antibody conjugates of doxorubicin prepared with branched linkers: A novel method for increasing the potency of doxorubicin immunoconjugates.

King HD, Yurgaitis D, Willner D, Firestone RA, Yang MB, Lasch SJ, Hellström KE, Trail PA. King HD, et al. Among authors: trail pa. Bioconjug Chem. 1999 Mar-Apr;10(2):279-88. doi: 10.1021/bc980100i. Bioconjug Chem. 1999. PMID: 10077478

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