Dwek RA - Search Results

1

Treatment with miglustat reverses the lipid-trafficking defect in Niemann-Pick disease type C.

Lachmann RH, te Vruchte D, Lloyd-Evans E, Reinkensmeier G, Sillence DJ, Fernandez-Guillen L, Dwek RA, Butters TD, Cox TM, Platt FM. Lachmann RH, et al. Among authors: dwek ra. Neurobiol Dis. 2004 Aug;16(3):654-8. doi: 10.1016/j.nbd.2004.05.002. Neurobiol Dis. 2004. PMID: 15262277

2

Glucosylceramide modulates membrane traffic along the endocytic pathway.

Sillence DJ, Puri V, Marks DL, Butters TD, Dwek RA, Pagano RE, Platt FM. Sillence DJ, et al. Among authors: dwek ra. J Lipid Res. 2002 Nov;43(11):1837-45. doi: 10.1194/jlr.m200232-jlr200. J Lipid Res. 2002. PMID: 12401882 Free article.

3

Therapeutic applications of imino sugars in lysosomal storage disorders.

Butters TD, Dwek RA, Platt FM. Butters TD, et al. Among authors: dwek ra. Curr Top Med Chem. 2003;3(5):561-74. doi: 10.2174/1568026033452483. Curr Top Med Chem. 2003. PMID: 12570866 Review.

4

Accumulation of glycosphingolipids in Niemann-Pick C disease disrupts endosomal transport.

te Vruchte D, Lloyd-Evans E, Veldman RJ, Neville DC, Dwek RA, Platt FM, van Blitterswijk WJ, Sillence DJ. te Vruchte D, et al. Among authors: dwek ra. J Biol Chem. 2004 Jun 18;279(25):26167-75. doi: 10.1074/jbc.M311591200. Epub 2004 Apr 12. J Biol Chem. 2004. PMID: 15078881 Free article.

5

Improved outcome of N-butyldeoxygalactonojirimycin-mediated substrate reduction therapy in a mouse model of Sandhoff disease.

Andersson U, Smith D, Jeyakumar M, Butters TD, Borja MC, Dwek RA, Platt FM. Andersson U, et al. Among authors: dwek ra. Neurobiol Dis. 2004 Aug;16(3):506-15. doi: 10.1016/j.nbd.2004.04.012. Neurobiol Dis. 2004. PMID: 15262262

6

Glycosphingolipid lysosomal storage diseases: therapy and pathogenesis.

Jeyakumar M, Butters TD, Dwek RA, Platt FM. Jeyakumar M, et al. Among authors: dwek ra. Neuropathol Appl Neurobiol. 2002 Oct;28(5):343-57. doi: 10.1046/j.1365-2990.2002.00422.x. Neuropathol Appl Neurobiol. 2002. PMID: 12366816 Review.

7

An inducible mouse model of late onset Tay-Sachs disease.

Jeyakumar M, Smith D, Eliott-Smith E, Cortina-Borja M, Reinkensmeier G, Butters TD, Lemm T, Sandhoff K, Perry VH, Dwek RA, Platt FM. Jeyakumar M, et al. Among authors: dwek ra. Neurobiol Dis. 2002 Aug;10(3):201-10. doi: 10.1006/nbdi.2002.0511. Neurobiol Dis. 2002. PMID: 12270683

8

Small-molecule therapeutics for the treatment of glycolipid lysosomal storage disorders.

Butters TD, Mellor HR, Narita K, Dwek RA, Platt FM. Butters TD, et al. Among authors: dwek ra. Philos Trans R Soc Lond B Biol Sci. 2003 May 29;358(1433):927-45. doi: 10.1098/rstb.2003.1278. Philos Trans R Soc Lond B Biol Sci. 2003. PMID: 12803927 Free PMC article. Review.

9

Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses.

Butters TD, Dwek RA, Platt FM. Butters TD, et al. Among authors: dwek ra. Glycobiology. 2005 Oct;15(10):43R-52R. doi: 10.1093/glycob/cwi076. Epub 2005 May 18. Glycobiology. 2005. PMID: 15901676 Review.

10

Storage solutions: treating lysosomal disorders of the brain.

Jeyakumar M, Dwek RA, Butters TD, Platt FM. Jeyakumar M, et al. Among authors: dwek ra. Nat Rev Neurosci. 2005 Sep;6(9):713-25. doi: 10.1038/nrn1725. Nat Rev Neurosci. 2005. PMID: 16049428 Review.

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