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The Kaposi's sarcoma-associated herpesvirus complement control protein mimics human molecular mechanisms for inhibition of the complement system.
Mark L, Lee WH, Spiller OB, Proctor D, Blackbourn DJ, Villoutreix BO, Blom AM. Mark L, et al. J Biol Chem. 2004 Oct 22;279(43):45093-101. doi: 10.1074/jbc.M407558200. Epub 2004 Aug 10. J Biol Chem. 2004. PMID: 15304516 Free article.
Previously, we reported that the KSHV complement control protein (KCP) encoded within the viral genome is a potent regulator of the complement system; it acts both as a cofactor for factor I and accelerates decay of the C3 convertases (Spiller, O. B., Blackbourn, D. J., Mark
Previously, we reported that the KSHV complement control protein (KCP) encoded within the viral genome is a potent regulator of the compleme …
526 results