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In vitro IL-12 treatment of peripheral blood mononuclear cells from patients with leukemia or myelodysplastic syndromes: increase in cytotoxicity and reduction in WT1 gene expression.
Pan L, Ohnishi K, Zhang WJ, Yoshida H, Maksumova L, Muratkhodjaev F, Shigeno K, Nakamura S, Luo JM, Hao HL, Fujisawa S, Naito K, Shinjo K, Takeshita A, Ohno R. Pan L, et al. Among authors: fujisawa s. Leukemia. 2000 Sep;14(9):1634-41. doi: 10.1038/sj.leu.2401872. Leukemia. 2000. PMID: 10995011
Pharmacokinetics of arsenic species in Japanese patients with relapsed or refractory acute promyelocytic leukemia treated with arsenic trioxide.
Fujisawa S, Ohno R, Shigeno K, Sahara N, Nakamura S, Naito K, Kobayashi M, Shinjo K, Takeshita A, Suzuki Y, Hashimoto H, Kinoshita K, Shimoya M, Kaise T, Ohnishi K. Fujisawa S, et al. Cancer Chemother Pharmacol. 2007 Mar;59(4):485-93. doi: 10.1007/s00280-006-0288-4. Epub 2006 Aug 26. Cancer Chemother Pharmacol. 2007. PMID: 16937107
Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms.
Hirano I, Nakamura S, Yokota D, Ono T, Shigeno K, Fujisawa S, Shinjo K, Ohnishi K. Hirano I, et al. Among authors: fujisawa s. J Biol Chem. 2009 Aug 14;284(33):22155-22165. doi: 10.1074/jbc.M808182200. Epub 2009 Mar 4. J Biol Chem. 2009. PMID: 19261608 Free PMC article.
Spicamycin and KRN5500 induce apoptosis in myeloid and lymphoid cell lines with down-regulation of bcl-2 expression and modulation of promyelocytic leukemia protein.
Zhang WJ, Ohnishi K, Yoshida H, Pan L, Maksumova L, Muratkhodjaev F, Luo JM, Shigeno K, Fujisawa S, Naito K, Nakamura S, Shinjo K, Takeshita A, Ohno R. Zhang WJ, et al. Among authors: fujisawa s. Jpn J Cancer Res. 2000 Jun;91(6):604-11. doi: 10.1111/j.1349-7006.2000.tb00988.x. Jpn J Cancer Res. 2000. PMID: 10874212 Free PMC article.
759 results