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Amino acid substitutions can influence the natural killer (NK)-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clones.
Biassoni R, Falco M, Cambiaggi A, Costa P, Verdiani S, Pende D, Conte R, Di Donato C, Parham P, Moretta L. Biassoni R, et al. Among authors: falco m. J Exp Med. 1995 Aug 1;182(2):605-9. doi: 10.1084/jem.182.2.605. J Exp Med. 1995. PMID: 7629517 Free PMC article.
The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.
Biassoni R, Cantoni C, Falco M, Verdiani S, Bottino C, Vitale M, Conte R, Poggi A, Moretta A, Moretta L. Biassoni R, et al. Among authors: falco m. J Exp Med. 1996 Feb 1;183(2):645-50. doi: 10.1084/jem.183.2.645. J Exp Med. 1996. PMID: 8627176 Free PMC article.
The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.
Pende D, Biassoni R, Cantoni C, Verdiani S, Falco M, di Donato C, Accame L, Bottino C, Moretta A, Moretta L. Pende D, et al. Among authors: falco m. J Exp Med. 1996 Aug 1;184(2):505-18. doi: 10.1084/jem.184.2.505. J Exp Med. 1996. PMID: 8760804 Free PMC article.
A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation.
Bottino C, Sivori S, Vitale M, Cantoni C, Falco M, Pende D, Morelli L, Augugliaro R, Semenzato G, Biassoni R, Moretta L, Moretta A. Bottino C, et al. Among authors: falco m. Eur J Immunol. 1996 Aug;26(8):1816-24. doi: 10.1002/eji.1830260823. Eur J Immunol. 1996. PMID: 8765026
579 results