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Page 1
Mcl-1 regulation and its role in multiple myeloma.
Le Gouill S, Podar K, Harousseau JL, Anderson KC. Le Gouill S, et al. Cell Cycle. 2004 Oct;3(10):1259-62. doi: 10.4161/cc.3.10.1196. Epub 2004 Oct 3. Cell Cycle. 2004. PMID: 15467463 Review.
Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis.
Ishitsuka K, Hideshima T, Hamasaki M, Raje N, Kumar S, Hideshima H, Shiraishi N, Yasui H, Roccaro AM, Richardson P, Podar K, Le Gouill S, Chauhan D, Tamura K, Arbiser J, Anderson KC. Ishitsuka K, et al. Among authors: le gouill s. Blood. 2005 Sep 1;106(5):1794-800. doi: 10.1182/blood-2005-01-0346. Epub 2005 May 3. Blood. 2005. PMID: 15870175 Free PMC article.
Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway.
Ishitsuka K, Hideshima T, Hamasaki M, Raje N, Kumar S, Podar K, Le Gouill S, Shiraishi N, Yasui H, Roccaro AM, Tai YZ, Chauhan D, Fram R, Tamura K, Jain J, Anderson KC. Ishitsuka K, et al. Among authors: le gouill s. Oncogene. 2005 Sep 1;24(38):5888-96. doi: 10.1038/sj.onc.1208739. Oncogene. 2005. PMID: 15940263
Janus kinase inhibitor INCB20 has antiproliferative and apoptotic effects on human myeloma cells in vitro and in vivo.
Burger R, Le Gouill S, Tai YT, Shringarpure R, Tassone P, Neri P, Podar K, Catley L, Hideshima T, Chauhan D, Caulder E, Neilan CL, Vaddi K, Li J, Gramatzki M, Fridman JS, Anderson KC. Burger R, et al. Among authors: le gouill s. Mol Cancer Ther. 2009 Jan;8(1):26-35. doi: 10.1158/1535-7163.MCT-08-0149. Mol Cancer Ther. 2009. PMID: 19139110 Free PMC article.
ABT-737 is highly effective against molecular subgroups of multiple myeloma.
Bodet L, Gomez-Bougie P, Touzeau C, Dousset C, Descamps G, Maïga S, Avet-Loiseau H, Bataille R, Moreau P, Le Gouill S, Pellat-Deceunynck C, Amiot M. Bodet L, et al. Among authors: le gouill s. Blood. 2011 Oct 6;118(14):3901-10. doi: 10.1182/blood-2010-11-317438. Epub 2011 Aug 11. Blood. 2011. PMID: 21835956 Free article.
269 results