Backus C - Search Results

1

Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons.

Leinninger GM, Backus C, Uhler MD, Lentz SI, Feldman EL. Leinninger GM, et al. Among authors: backus c. FASEB J. 2004 Oct;18(13):1544-6. doi: 10.1096/fj.04-1581fje. Epub 2004 Aug 19. FASEB J. 2004. PMID: 15319368 Free article.

2

Short-term hyperglycemia produces oxidative damage and apoptosis in neurons.

Vincent AM, McLean LL, Backus C, Feldman EL. Vincent AM, et al. Among authors: backus c. FASEB J. 2005 Apr;19(6):638-40. doi: 10.1096/fj.04-2513fje. Epub 2005 Jan 27. FASEB J. 2005. PMID: 15677696

3

Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1.

Leinninger GM, Backus C, Sastry AM, Yi YB, Wang CW, Feldman EL. Leinninger GM, et al. Among authors: backus c. Neurobiol Dis. 2006 Jul;23(1):11-22. doi: 10.1016/j.nbd.2006.01.017. Epub 2006 May 8. Neurobiol Dis. 2006. PMID: 16684605

4

Cortical neurons develop insulin resistance and blunted Akt signaling: a potential mechanism contributing to enhanced ischemic injury in diabetes.

Kim B, Sullivan KA, Backus C, Feldman EL. Kim B, et al. Among authors: backus c. Antioxid Redox Signal. 2011 May 15;14(10):1829-39. doi: 10.1089/ars.2010.3816. Epub 2011 Mar 8. Antioxid Redox Signal. 2011. PMID: 21194385 Free PMC article.

5

Diabetes regulates mitochondrial biogenesis and fission in mouse neurons.

Edwards JL, Quattrini A, Lentz SI, Figueroa-Romero C, Cerri F, Backus C, Hong Y, Feldman EL. Edwards JL, et al. Among authors: backus c. Diabetologia. 2010 Jan;53(1):160-9. doi: 10.1007/s00125-009-1553-y. Epub 2009 Oct 22. Diabetologia. 2010. PMID: 19847394 Free PMC article.

6

Identification of candidate drugs for the treatment of ALS.

Vincent AM, Backus C, Taubman AA, Feldman EL. Vincent AM, et al. Among authors: backus c. Amyotroph Lateral Scler Other Motor Neuron Disord. 2005 Mar;6(1):29-36. doi: 10.1080/14660820510026171. Amyotroph Lateral Scler Other Motor Neuron Disord. 2005. PMID: 16036423

7

Cell culture modeling to test therapies against hyperglycemia-mediated oxidative stress and injury.

Vincent AM, Stevens MJ, Backus C, McLean LL, Feldman EL. Vincent AM, et al. Among authors: backus c. Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1494-506. doi: 10.1089/ars.2005.7.1494. Antioxid Redox Signal. 2005. PMID: 16356113 Free article.

8

Receptor for advanced glycation end products activation injures primary sensory neurons via oxidative stress.

Vincent AM, Perrone L, Sullivan KA, Backus C, Sastry AM, Lastoskie C, Feldman EL. Vincent AM, et al. Among authors: backus c. Endocrinology. 2007 Feb;148(2):548-58. doi: 10.1210/en.2006-0073. Epub 2006 Nov 9. Endocrinology. 2007. PMID: 17095586

9

SOD2 protects neurons from injury in cell culture and animal models of diabetic neuropathy.

Vincent AM, Russell JW, Sullivan KA, Backus C, Hayes JM, McLean LL, Feldman EL. Vincent AM, et al. Among authors: backus c. Exp Neurol. 2007 Dec;208(2):216-27. doi: 10.1016/j.expneurol.2007.07.017. Epub 2007 Aug 3. Exp Neurol. 2007. PMID: 17927981 Free PMC article.

10

The pleotrophic effects of insulin-like growth factor-I on human spinal cord neural progenitor cells.

Lunn JS, Pacut C, Backus C, Hong Y, Johe K, Hefferan M, Marsala M, Feldman EL. Lunn JS, et al. Among authors: backus c. Stem Cells Dev. 2010 Dec;19(12):1983-93. doi: 10.1089/scd.2010.0003. Epub 2010 Oct 7. Stem Cells Dev. 2010. PMID: 20406098 Free article.

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