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Site of pegylation and polyethylene glycol molecule size attenuate interferon-alpha antiviral and antiproliferative activities through the JAK/STAT signaling pathway.
Grace MJ, Lee S, Bradshaw S, Chapman J, Spond J, Cox S, Delorenzo M, Brassard D, Wylie D, Cannon-Carlson S, Cullen C, Indelicato S, Voloch M, Bordens R. Grace MJ, et al. J Biol Chem. 2005 Feb 25;280(8):6327-36. doi: 10.1074/jbc.M412134200. Epub 2004 Dec 13. J Biol Chem. 2005. PMID: 15596441 Free article.
Pegylated IFNs for chronic hepatitis C: an update.
Grace MJ, Cutler DL, Bordens RW. Grace MJ, et al. Expert Opin Drug Deliv. 2005 Mar;2(2):219-26. doi: 10.1517/17425247.2.2.219. Expert Opin Drug Deliv. 2005. PMID: 16296749 Review.
Interferon-alpha as an immunotherapeutic protein.
Brassard DL, Grace MJ, Bordens RW. Brassard DL, et al. Among authors: grace mj. J Leukoc Biol. 2002 Apr;71(4):565-81. J Leukoc Biol. 2002. PMID: 11927642 Review.
45 results