Luzhetskyy A - Search Results

1

Generation of Streptomyces globisporus SMY622 strain with increased landomycin E production and it's initial characterization.

Gromyko O, Rebets Y, Ostash B, Luzhetskyy A, Fukuhara M, Bechthold A, Nakamura T, Fedorenko V. Gromyko O, et al. Among authors: luzhetskyy a. J Antibiot (Tokyo). 2004 Jun;57(6):383-9. doi: 10.7164/antibiotics.57.383. J Antibiot (Tokyo). 2004. PMID: 15323127 Free article.

2

Heterologous Production and Biosynthesis of Threonine-16:0dioic acids with a Hydroxamate Moiety.

Stierhof M, Myronovskyi M, Zapp J, Luzhetskyy A. Stierhof M, et al. Among authors: luzhetskyy a. J Nat Prod. 2023 Oct 27;86(10):2258-2269. doi: 10.1021/acs.jnatprod.3c00097. Epub 2023 Sep 20. J Nat Prod. 2023. PMID: 37728876 Free PMC article.

3

Production of landomycins in Streptomyces globisporus 1912 and S cyanogenus S136 is regulated by genes encoding putative transcriptional activators.

Rebets Y, Ostash B, Luzhetskyy A, Hoffmeister D, Brana A, Mendez C, Salas JA, Bechthold A, Fedorenko V. Rebets Y, et al. Among authors: luzhetskyy a. FEMS Microbiol Lett. 2003 May 16;222(1):149-53. doi: 10.1016/S0378-1097(03)00258-1. FEMS Microbiol Lett. 2003. PMID: 12757959

4

Targeted disruption of Streptomyces globisporus lndF and lndL cyclase genes involved in landomycin E biosynthesis.

Ostash B, Rebets Y, Yuskevich V, Luzhetskyy A, Tkachenko V, Fedorenko V. Ostash B, et al. Among authors: luzhetskyy a. Folia Microbiol (Praha). 2003;48(4):484-8. doi: 10.1007/BF02931329. Folia Microbiol (Praha). 2003. PMID: 14533479

5

Expression of the landomycin biosynthetic gene cluster in a PKS mutant of Streptomyces fradiae is dependent on the coexpression of a putative transcriptional activator gene.

von Mulert U, Luzhetskyy A, Hofmann C, Mayer A, Bechthold A. von Mulert U, et al. Among authors: luzhetskyy a. FEMS Microbiol Lett. 2004 Jan 15;230(1):91-7. doi: 10.1016/S0378-1097(03)00861-9. FEMS Microbiol Lett. 2004. PMID: 14734170

6

Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus.

Ostash B, Rix U, Rix LL, Liu T, Lombo F, Luzhetskyy A, Gromyko O, Wang C, Braña AF, Méndez C, Salas JA, Fedorenko V, Rohr J. Ostash B, et al. Among authors: luzhetskyy a. Chem Biol. 2004 Apr;11(4):547-55. doi: 10.1016/j.chembiol.2004.03.011. Chem Biol. 2004. PMID: 15123249

7

Function of lanGT3, a glycosyltransferase gene involved in landomycin A biosynthesis.

Luzhetskyy A, Liu T, Fedoryshyn M, Ostash B, Fedorenko V, Rohr J, Bechthold A. Luzhetskyy A, et al. Chembiochem. 2004 Nov 5;5(11):1567-70. doi: 10.1002/cbic.200400123. Chembiochem. 2004. PMID: 15515090

8

DNA-binding activity of LndI protein and temporal expression of the gene that upregulates landomycin E production in Streptomyces globisporus 1912.

Rebets Y, Ostash B, Luzhetskyy A, Kushnir S, Fukuhara M, Bechthold A, Nashimoto M, Nakamura T, Fedorenko V. Rebets Y, et al. Among authors: luzhetskyy a. Microbiology (Reading). 2005 Jan;151(Pt 1):281-290. doi: 10.1099/mic.0.27244-0. Microbiology (Reading). 2005. PMID: 15632445 Free article.

9

Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycinone.

Zhu L, Ostash B, Rix U, Nur-E-Alam M, Mayers A, Luzhetskyy A, Mendez C, Salas JA, Bechthold A, Fedorenko V, Rohr J. Zhu L, et al. Among authors: luzhetskyy a. J Org Chem. 2005 Jan 21;70(2):631-8. doi: 10.1021/jo0483623. J Org Chem. 2005. PMID: 15651811 Free PMC article.

10

Generation of novel landomycins M and O through targeted gene disruption.

Luzhetskyy A, Zhu L, Gibson M, Fedoryshyn M, Dürr C, Hofmann C, Hoffmeister D, Ostash B, Mattingly C, Adams V, Fedorenko V, Rohr J, Bechthold A. Luzhetskyy A, et al. Chembiochem. 2005 Apr;6(4):675-8. doi: 10.1002/cbic.200400316. Chembiochem. 2005. PMID: 15812784

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