Carrassa L - Search Results

1

Chk1, but not Chk2, is involved in the cellular response to DNA damaging agents: differential activity in cells expressing or not p53.

Carrassa L, Broggini M, Erba E, Damia G. Carrassa L, et al. Cell Cycle. 2004 Sep;3(9):1177-81. Epub 2004 Sep 13. Cell Cycle. 2004. PMID: 15326376

2

Characterization of the 5'flanking region of the human Chk1 gene: identification of E2F1 functional sites.

Carrassa L, Broggini M, Vikhanskaya F, Damia G. Carrassa L, et al. Cell Cycle. 2003 Nov-Dec;2(6):604-9. Cell Cycle. 2003. PMID: 14504477

3

Checkpoint kinase 1 down-regulation by an inducible small interfering RNA expression system sensitized in vivo tumors to treatment with 5-fluorouracil.

Ganzinelli M, Carrassa L, Crippa F, Tavecchio M, Broggini M, Damia G. Ganzinelli M, et al. Among authors: carrassa l. Clin Cancer Res. 2008 Aug 15;14(16):5131-41. doi: 10.1158/1078-0432.CCR-08-0304. Clin Cancer Res. 2008. PMID: 18698031

4

U2OS cells lacking Chk1 undergo aberrant mitosis and fail to activate the spindle checkpoint.

Carrassa L, Sanchez Y, Erba E, Damia G. Carrassa L, et al. J Cell Mol Med. 2009 Aug;13(8A):1565-76. doi: 10.1111/j.1582-4934.2009.00362.x. J Cell Mol Med. 2009. PMID: 19778378 Free PMC article.

5

Role of Chk1 in the differentiation program of hematopoietic stem cells.

Carrassa L, Montelatici E, Lazzari L, Zangrossi S, Simone M, Broggini M, Damia G. Carrassa L, et al. Cell Mol Life Sci. 2010 May;67(10):1713-22. doi: 10.1007/s00018-010-0274-1. Epub 2010 Feb 10. Cell Mol Life Sci. 2010. PMID: 20146081 Free PMC article.

6

Unleashing Chk1 in cancer therapy.

Carrassa L, Damia G. Carrassa L, et al. Cell Cycle. 2011 Jul 1;10(13):2121-8. doi: 10.4161/cc.10.13.16398. Epub 2011 Jul 1. Cell Cycle. 2011. PMID: 21610326 Review.

7

Combined inhibition of Chk1 and Wee1: in vitro synergistic effect translates to tumor growth inhibition in vivo.

Carrassa L, Chilà R, Lupi M, Ricci F, Celenza C, Mazzoletti M, Broggini M, Damia G. Carrassa L, et al. Cell Cycle. 2012 Jul 1;11(13):2507-17. doi: 10.4161/cc.20899. Epub 2012 Jul 1. Cell Cycle. 2012. PMID: 22713237

8

Chk1-Mad2 interaction: a crosslink between the DNA damage checkpoint and the mitotic spindle checkpoint.

Chilà R, Celenza C, Lupi M, Damia G, Carrassa L. Chilà R, et al. Among authors: carrassa l. Cell Cycle. 2013 Apr 1;12(7):1083-90. doi: 10.4161/cc.24090. Epub 2013 Mar 1. Cell Cycle. 2013. PMID: 23454898 Free PMC article.

9

Structure-based discovery of the first allosteric inhibitors of cyclin-dependent kinase 2.

Rastelli G, Anighoro A, Chripkova M, Carrassa L, Broggini M. Rastelli G, et al. Among authors: carrassa l. Cell Cycle. 2014;13(14):2296-305. doi: 10.4161/cc.29295. Epub 2014 Jun 9. Cell Cycle. 2014. PMID: 24911186 Free PMC article.

10

DNA damage response inhibitors: Mechanisms and potential applications in cancer therapy.

Carrassa L, Damia G. Carrassa L, et al. Cancer Treat Rev. 2017 Nov;60:139-151. doi: 10.1016/j.ctrv.2017.08.013. Epub 2017 Sep 19. Cancer Treat Rev. 2017. PMID: 28961555 Review.

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