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Near completely humanized liver in mice shows human-type metabolic responses to drugs.
Tateno C, Yoshizane Y, Saito N, Kataoka M, Utoh R, Yamasaki C, Tachibana A, Soeno Y, Asahina K, Hino H, Asahara T, Yokoi T, Furukawa T, Yoshizato K. Tateno C, et al. Among authors: kataoka m. Am J Pathol. 2004 Sep;165(3):901-12. doi: 10.1016/S0002-9440(10)63352-4. Am J Pathol. 2004. PMID: 15331414 Free PMC article.
Expression of human cytochromes P450 in chimeric mice with humanized liver.
Katoh M, Matsui T, Nakajima M, Tateno C, Kataoka M, Soeno Y, Horie T, Iwasaki K, Yoshizato K, Yokoi T. Katoh M, et al. Among authors: kataoka m. Drug Metab Dispos. 2004 Dec;32(12):1402-10. doi: 10.1124/dmd.104.001347. Epub 2004 Sep 21. Drug Metab Dispos. 2004. PMID: 15383493
1,894 results