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A synthetic peptide blocking the apolipoprotein E/beta-amyloid binding mitigates beta-amyloid toxicity and fibril formation in vitro and reduces beta-amyloid plaques in transgenic mice.
Sadowski M, Pankiewicz J, Scholtzova H, Ripellino JA, Li Y, Schmidt SD, Mathews PM, Fryer JD, Holtzman DM, Sigurdsson EM, Wisniewski T. Sadowski M, et al. Among authors: scholtzova h. Am J Pathol. 2004 Sep;165(3):937-48. doi: 10.1016/s0002-9440(10)63355-x. Am J Pathol. 2004. PMID: 15331417 Free PMC article.
Targeting prion amyloid deposits in vivo.
Sadowski M, Pankiewicz J, Scholtzova H, Tsai J, Li Y, Carp RI, Meeker HC, Gambetti P, Debnath M, Mathis CA, Shao L, Gan WB, Klunk WE, Wisniewski T. Sadowski M, et al. Among authors: scholtzova h. J Neuropathol Exp Neurol. 2004 Jul;63(7):775-84. doi: 10.1093/jnen/63.7.775. J Neuropathol Exp Neurol. 2004. PMID: 15290902
A non-toxic ligand for voxel-based MRI analysis of plaques in AD transgenic mice.
Sigurdsson EM, Wadghiri YZ, Mosconi L, Blind JA, Knudsen E, Asuni A, Scholtzova H, Tsui WH, Li Y, Sadowski M, Turnbull DH, de Leon MJ, Wisniewski T. Sigurdsson EM, et al. Among authors: scholtzova h. Neurobiol Aging. 2008 Jun;29(6):836-47. doi: 10.1016/j.neurobiolaging.2006.12.018. Epub 2007 Feb 8. Neurobiol Aging. 2008. PMID: 17291630 Free PMC article.
29 results