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Number of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH-2-/- mice.
Wenzel P, Hink U, Oelze M, Seeling A, Isse T, Bruns K, Steinhoff L, Brandt M, Kleschyov AL, Schulz E, Lange K, Weiner H, Lehmann J, Lackner KJ, Kawamoto T, Münzel T, Daiber A. Wenzel P, et al. Among authors: kleschyov al. Br J Pharmacol. 2007 Feb;150(4):526-33. doi: 10.1038/sj.bjp.0707116. Epub 2007 Jan 15. Br J Pharmacol. 2007. PMID: 17220910 Free PMC article.
Nebivolol prevents vascular NOS III uncoupling in experimental hyperlipidemia and inhibits NADPH oxidase activity in inflammatory cells.
Mollnau H, Schulz E, Daiber A, Baldus S, Oelze M, August M, Wendt M, Walter U, Geiger C, Agrawal R, Kleschyov AL, Meinertz T, Münzel T. Mollnau H, et al. Among authors: kleschyov al. Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):615-21. doi: 10.1161/01.ATV.0000065234.70518.26. Epub 2003 Mar 6. Arterioscler Thromb Vasc Biol. 2003. PMID: 12692005
Does nitric oxide mediate the vasodilator activity of nitroglycerin?
Kleschyov AL, Oelze M, Daiber A, Huang Y, Mollnau H, Schulz E, Sydow K, Fichtlscherer B, Mülsch A, Münzel T. Kleschyov AL, et al. Circ Res. 2003 Oct 31;93(9):e104-12. doi: 10.1161/01.RES.0000100067.62876.50. Epub 2003 Oct 9. Circ Res. 2003. PMID: 14551241
Sirolimus-induced vascular dysfunction. Increased mitochondrial and nicotinamide adenosine dinucleotide phosphate oxidase-dependent superoxide production and decreased vascular nitric oxide formation.
Jabs A, Göbel S, Wenzel P, Kleschyov AL, Hortmann M, Oelze M, Daiber A, Münzel T. Jabs A, et al. Among authors: kleschyov al. J Am Coll Cardiol. 2008 Jun 3;51(22):2130-8. doi: 10.1016/j.jacc.2008.01.058. J Am Coll Cardiol. 2008. PMID: 18510959 Free article.
Cyclooxygenase 2-selective and nonselective nonsteroidal anti-inflammatory drugs induce oxidative stress by up-regulating vascular NADPH oxidases.
Li H, Hortmann M, Daiber A, Oelze M, Ostad MA, Schwarz PM, Xu H, Xia N, Kleschyov AL, Mang C, Warnholtz A, Münzel T, Förstermann U. Li H, et al. Among authors: kleschyov al. J Pharmacol Exp Ther. 2008 Sep;326(3):745-53. doi: 10.1124/jpet.108.139030. Epub 2008 Jun 11. J Pharmacol Exp Ther. 2008. PMID: 18550689
61 results