Kinghorn KJ - Search Results

1

Polymerisation underlies alpha1-antitrypsin deficiency, dementia and other serpinopathies.

Lomas DA, Belorgey D, Mallya M, Onda M, Kinghorn KJ, Sharp LK, Phillips RL, Page R, Crowther DC, Miranda E. Lomas DA, et al. Among authors: kinghorn kj. Front Biosci. 2004 Sep 1;9:2873-91. doi: 10.2741/1444. Front Biosci. 2004. PMID: 15353322 Review.

2

Molecular mousetraps and the serpinopathies.

Lomas DA, Belorgey D, Mallya M, Miranda E, Kinghorn KJ, Sharp LK, Phillips RL, Page R, Robertson AS, Crowther DC. Lomas DA, et al. Among authors: kinghorn kj. Biochem Soc Trans. 2005 Apr;33(Pt 2):321-30. doi: 10.1042/BST0330321. Biochem Soc Trans. 2005. PMID: 15787598

3

Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies.

Crowther DC, Belorgey D, Miranda E, Kinghorn KJ, Sharp LK, Lomas DA. Crowther DC, et al. Among authors: kinghorn kj. Eur J Hum Genet. 2004 Mar;12(3):167-72. doi: 10.1038/sj.ejhg.5201127. Eur J Hum Genet. 2004. PMID: 14694355 Review.

4

Sugar and alcohol molecules provide a therapeutic strategy for the serpinopathies that cause dementia and cirrhosis.

Sharp LK, Mallya M, Kinghorn KJ, Wang Z, Crowther DC, Huntington JA, Belorgey D, Lomas DA. Sharp LK, et al. Among authors: kinghorn kj. FEBS J. 2006 Jun;273(11):2540-52. doi: 10.1111/j.1742-4658.2006.05262.x. FEBS J. 2006. PMID: 16704419 Free article.

5

Intraneuronal Abeta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease.

Crowther DC, Kinghorn KJ, Miranda E, Page R, Curry JA, Duthie FA, Gubb DC, Lomas DA. Crowther DC, et al. Among authors: kinghorn kj. Neuroscience. 2005;132(1):123-35. doi: 10.1016/j.neuroscience.2004.12.025. Neuroscience. 2005. PMID: 15780472

6

Therapeutic targets from a Drosophila model of Alzheimer's disease.

Crowther DC, Kinghorn KJ, Page R, Lomas DA. Crowther DC, et al. Among authors: kinghorn kj. Curr Opin Pharmacol. 2004 Oct;4(5):513-6. doi: 10.1016/j.coph.2004.07.001. Curr Opin Pharmacol. 2004. PMID: 15351357 Review.

7

Neuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer disease.

Kinghorn KJ, Crowther DC, Sharp LK, Nerelius C, Davis RL, Chang HT, Green C, Gubb DC, Johansson J, Lomas DA. Kinghorn KJ, et al. J Biol Chem. 2006 Sep 29;281(39):29268-77. doi: 10.1074/jbc.M600690200. Epub 2006 Jul 17. J Biol Chem. 2006. PMID: 16849336 Free article.

8

A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin.

Kinghorn KJ, Grönke S, Castillo-Quan JI, Woodling NS, Li L, Sirka E, Gegg M, Mills K, Hardy J, Bjedov I, Partridge L. Kinghorn KJ, et al. J Neurosci. 2016 Nov 16;36(46):11654-11670. doi: 10.1523/JNEUROSCI.4527-15.2016. J Neurosci. 2016. PMID: 27852774 Free PMC article.

9

Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis.

Castillo-Quan JI, Li L, Kinghorn KJ, Ivanov DK, Tain LS, Slack C, Kerr F, Nespital T, Thornton J, Hardy J, Bjedov I, Partridge L. Castillo-Quan JI, et al. Among authors: kinghorn kj. Cell Rep. 2016 Apr 19;15(3):638-650. doi: 10.1016/j.celrep.2016.03.041. Epub 2016 Apr 7. Cell Rep. 2016. PMID: 27068460 Free PMC article.

10

Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila.

Bjedov I, Cochemé HM, Foley A, Wieser D, Woodling NS, Castillo-Quan JI, Norvaisas P, Lujan C, Regan JC, Toivonen JM, Murphy MP, Thornton J, Kinghorn KJ, Neufeld TP, Cabreiro F, Partridge L. Bjedov I, et al. Among authors: kinghorn kj. PLoS Genet. 2020 Nov 30;16(11):e1009083. doi: 10.1371/journal.pgen.1009083. eCollection 2020 Nov. PLoS Genet. 2020. PMID: 33253201 Free PMC article.

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