Lomas DA - Search Results

1

Polymerisation underlies alpha1-antitrypsin deficiency, dementia and other serpinopathies.

Lomas DA, Belorgey D, Mallya M, Onda M, Kinghorn KJ, Sharp LK, Phillips RL, Page R, Crowther DC, Miranda E. Lomas DA, et al. Front Biosci. 2004 Sep 1;9:2873-91. doi: 10.2741/1444. Front Biosci. 2004. PMID: 15353322 Review.

2

Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies.

Crowther DC, Belorgey D, Miranda E, Kinghorn KJ, Sharp LK, Lomas DA. Crowther DC, et al. Among authors: lomas da. Eur J Hum Genet. 2004 Mar;12(3):167-72. doi: 10.1038/sj.ejhg.5201127. Eur J Hum Genet. 2004. PMID: 14694355 Review.

3

Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB.

Belorgey D, Sharp LK, Crowther DC, Onda M, Johansson J, Lomas DA. Belorgey D, et al. Among authors: lomas da. Eur J Biochem. 2004 Aug;271(16):3360-7. doi: 10.1111/j.1432-1033.2004.04270.x. Eur J Biochem. 2004. PMID: 15291813 Free article.

4

Latent S49P neuroserpin forms polymers in the dementia familial encephalopathy with neuroserpin inclusion bodies.

Onda M, Belorgey D, Sharp LK, Lomas DA. Onda M, et al. Among authors: lomas da. J Biol Chem. 2005 Apr 8;280(14):13735-41. doi: 10.1074/jbc.M413282200. Epub 2005 Jan 21. J Biol Chem. 2005. PMID: 15664988 Free article.

5

Sugar and alcohol molecules provide a therapeutic strategy for the serpinopathies that cause dementia and cirrhosis.

Sharp LK, Mallya M, Kinghorn KJ, Wang Z, Crowther DC, Huntington JA, Belorgey D, Lomas DA. Sharp LK, et al. Among authors: lomas da. FEBS J. 2006 Jun;273(11):2540-52. doi: 10.1111/j.1742-4658.2006.05262.x. FEBS J. 2006. PMID: 16704419 Free article.

6

Small molecules block the polymerization of Z alpha1-antitrypsin and increase the clearance of intracellular aggregates.

Mallya M, Phillips RL, Saldanha SA, Gooptu B, Brown SC, Termine DJ, Shirvani AM, Wu Y, Sifers RN, Abagyan R, Lomas DA. Mallya M, et al. Among authors: lomas da. J Med Chem. 2007 Nov 1;50(22):5357-63. doi: 10.1021/jm070687z. Epub 2007 Oct 5. J Med Chem. 2007. PMID: 17918823 Free PMC article.

7

Protein misfolding and the serpinopathies.

Belorgey D, Hägglöf P, Karlsson-Li S, Lomas DA. Belorgey D, et al. Among authors: lomas da. Prion. 2007 Jan-Mar;1(1):15-20. doi: 10.4161/pri.1.1.3974. Epub 2007 Jan 6. Prion. 2007. PMID: 19164889 Free PMC article. Review.

8

alpha1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies.

Ekeowa UI, Gooptu B, Belorgey D, Hägglöf P, Karlsson-Li S, Miranda E, Pérez J, MacLeod I, Kroger H, Marciniak SJ, Crowther DC, Lomas DA. Ekeowa UI, et al. Among authors: lomas da. Clin Sci (Lond). 2009 May 14;116(12):837-50. doi: 10.1042/CS20080484. Clin Sci (Lond). 2009. PMID: 19426146 Review.

9

pH-dependent stability of neuroserpin is mediated by histidines 119 and 138; implications for the control of beta-sheet A and polymerization.

Belorgey D, Hägglöf P, Onda M, Lomas DA. Belorgey D, et al. Among authors: lomas da. Protein Sci. 2010 Feb;19(2):220-8. doi: 10.1002/pro.299. Protein Sci. 2010. PMID: 19953505 Free PMC article.

10

Unravelling the twists and turns of the serpinopathies.

Roussel BD, Irving JA, Ekeowa UI, Belorgey D, Haq I, Ordóñez A, Kruppa AJ, Duvoix A, Rashid ST, Crowther DC, Marciniak SJ, Lomas DA. Roussel BD, et al. Among authors: lomas da. FEBS J. 2011 Oct;278(20):3859-67. doi: 10.1111/j.1742-4658.2011.08201.x. Epub 2011 Jun 20. FEBS J. 2011. PMID: 21624056 Free article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

352 results

Search Page

Filters