Koftis TV - Search Results

1

Structural revision and total synthesis of azaspiracid-1, part 1: intelligence gathering and tentative proposal.

Nicolaou KC, Vyskocil S, Koftis TV, Yamada YM, Ling T, Chen DY, Tang W, Petrovic G, Frederick MO, Li Y, Satake M. Nicolaou KC, et al. Among authors: koftis tv. Angew Chem Int Ed Engl. 2004 Aug 20;43(33):4312-8. doi: 10.1002/anie.200460695. Angew Chem Int Ed Engl. 2004. PMID: 15368380 No abstract available.

2

Total synthesis of the proposed azaspiracid-1 structure, part 1: construction of the enantiomerically pure C1-C20, C21-C27, and C28-C40 fragments.

Nicolaou KC, Li Y, Uesaka N, Koftis TV, Vyskocil S, Ling T, Govindasamy M, Qian W, Bernal F, Chen DY. Nicolaou KC, et al. Among authors: koftis tv. Angew Chem Int Ed Engl. 2003 Aug 11;42(31):3643-8. doi: 10.1002/anie.200351825. Angew Chem Int Ed Engl. 2003. PMID: 12916036 No abstract available.

3

Total synthesis of the proposed azaspiracid-1 structure, part 2: coupling of the C1-C20, C21-C27, and C28-C40 fragments and completion of the synthesis.

Nicolaou KC, Chen DY, Li Y, Qian W, Ling T, Vyskocil S, Koftis TV, Govindasamy M, Uesaka N. Nicolaou KC, et al. Among authors: koftis tv. Angew Chem Int Ed Engl. 2003 Aug 11;42(31):3649-53. doi: 10.1002/anie.200351826. Angew Chem Int Ed Engl. 2003. PMID: 12916037 No abstract available.

4

Structural revision and total synthesis of azaspiracid-1, part 2: definition of the ABCD domain and total synthesis.

Nicolaou KC, Koftis TV, Vyskocil S, Petrovic G, Ling T, Yamada YM, Tang W, Frederick MO. Nicolaou KC, et al. Among authors: koftis tv. Angew Chem Int Ed Engl. 2004 Aug 20;43(33):4318-24. doi: 10.1002/anie.200460696. Angew Chem Int Ed Engl. 2004. PMID: 15368381 No abstract available.

5

Studies toward the synthesis of azadirachtin, part 2: construction of fully functionalized ABCD ring frameworks and unusual intramolecular reactions induced by close-proximity effects.

Nicolaou KC, Sasmal PK, Koftis TV, Converso A, Loizidou E, Kaiser F, Roecker AJ, Dellios CC, Sun XW, Petrovic G. Nicolaou KC, et al. Among authors: koftis tv. Angew Chem Int Ed Engl. 2005 May 30;44(22):3447-52. doi: 10.1002/anie.200500217. Angew Chem Int Ed Engl. 2005. PMID: 15849805 No abstract available.

6

Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure.

Nicolaou KC, Pihko PM, Bernal F, Frederick MO, Qian W, Uesaka N, Diedrichs N, Hinrichs J, Koftis TV, Loizidou E, Petrovic G, Rodriquez M, Sarlah D, Zou N. Nicolaou KC, et al. Among authors: koftis tv. J Am Chem Soc. 2006 Feb 22;128(7):2244-57. doi: 10.1021/ja0547477. J Am Chem Soc. 2006. PMID: 16478178

7

Total synthesis and structural elucidation of azaspiracid-1. Synthesis-based analysis of originally proposed structures and indication of their non-identity to the natural product.

Nicolaou KC, Chen DY, Li Y, Uesaka N, Petrovic G, Koftis TV, Bernal F, Frederick MO, Govindasamy M, Ling T, Pihko PM, Tang W, Vyskocil S. Nicolaou KC, et al. Among authors: koftis tv. J Am Chem Soc. 2006 Feb 22;128(7):2258-67. doi: 10.1021/ja054748z. J Am Chem Soc. 2006. PMID: 16478179

8

Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1.

Nicolaou KC, Koftis TV, Vyskocil S, Petrovic G, Tang W, Frederick MO, Chen DY, Li Y, Ling T, Yamada YM. Nicolaou KC, et al. Among authors: koftis tv. J Am Chem Soc. 2006 Mar 8;128(9):2859-72. doi: 10.1021/ja054750q. J Am Chem Soc. 2006. PMID: 16506764

9

Second-generation total synthesis of azaspiracids-1, -2, and -3.

Nicolaou KC, Frederick MO, Loizidou EZ, Petrovic G, Cole KP, Koftis TV, Yamada YM. Nicolaou KC, et al. Among authors: koftis tv. Chem Asian J. 2006 Jul 17;1(1-2):245-63. doi: 10.1002/asia.200600059. Chem Asian J. 2006. PMID: 17441061

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