Lehrach H - Search Results

1

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.

Goehler H, Lalowski M, Stelzl U, Waelter S, Stroedicke M, Worm U, Droege A, Lindenberg KS, Knoblich M, Haenig C, Herbst M, Suopanki J, Scherzinger E, Abraham C, Bauer B, Hasenbank R, Fritzsche A, Ludewig AH, Büssow K, Coleman SH, Gutekunst CA, Landwehrmeyer BG, Lehrach H, Wanker EE. Goehler H, et al. Among authors: lehrach h. Mol Cell. 2004 Sep 24;15(6):853-65. doi: 10.1016/j.molcel.2004.09.016. Mol Cell. 2004. PMID: 15383276 Free article.

2

A human protein-protein interaction network: a resource for annotating the proteome.

Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE. Stelzl U, et al. Among authors: lehrach h. Cell. 2005 Sep 23;122(6):957-68. doi: 10.1016/j.cell.2005.08.029. Cell. 2005. PMID: 16169070 Free article.

3

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.

Scherzinger E, Lurz R, Turmaine M, Mangiarini L, Hollenbach B, Hasenbank R, Bates GP, Davies SW, Lehrach H, Wanker EE. Scherzinger E, et al. Among authors: lehrach h. Cell. 1997 Aug 8;90(3):549-58. doi: 10.1016/s0092-8674(00)80514-0. Cell. 1997. PMID: 9267034 Free article.

4

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates.

Sittler A, Wälter S, Wedemeyer N, Hasenbank R, Scherzinger E, Eickhoff H, Bates GP, Lehrach H, Wanker EE. Sittler A, et al. Among authors: lehrach h. Mol Cell. 1998 Oct;2(4):427-36. doi: 10.1016/s1097-2765(00)80142-2. Mol Cell. 1998. PMID: 9809064 Free article.

5

Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation.

Waelter S, Boeddrich A, Lurz R, Scherzinger E, Lueder G, Lehrach H, Wanker EE. Waelter S, et al. Among authors: lehrach h. Mol Biol Cell. 2001 May;12(5):1393-407. doi: 10.1091/mbc.12.5.1393. Mol Biol Cell. 2001. PMID: 11359930 Free PMC article.

6

The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis.

Waelter S, Scherzinger E, Hasenbank R, Nordhoff E, Lurz R, Goehler H, Gauss C, Sathasivam K, Bates GP, Lehrach H, Wanker EE. Waelter S, et al. Among authors: lehrach h. Hum Mol Genet. 2001 Aug 15;10(17):1807-17. doi: 10.1093/hmg/10.17.1807. Hum Mol Genet. 2001. PMID: 11532990

7

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system.

Wanker EE, Rovira C, Scherzinger E, Hasenbank R, Wälter S, Tait D, Colicelli J, Lehrach H. Wanker EE, et al. Among authors: lehrach h. Hum Mol Genet. 1997 Mar;6(3):487-95. doi: 10.1093/hmg/6.3.487. Hum Mol Genet. 1997. PMID: 9147654

8

Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease.

Busch A, Engemann S, Lurz R, Okazawa H, Lehrach H, Wanker EE. Busch A, et al. Among authors: lehrach h. J Biol Chem. 2003 Oct 17;278(42):41452-61. doi: 10.1074/jbc.M303354200. Epub 2003 Jul 29. J Biol Chem. 2003. PMID: 12888569 Free article.

9

Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay.

Heiser V, Engemann S, Bröcker W, Dunkel I, Boeddrich A, Waelter S, Nordhoff E, Lurz R, Schugardt N, Rautenberg S, Herhaus C, Barnickel G, Böttcher H, Lehrach H, Wanker EE. Heiser V, et al. Among authors: lehrach h. Proc Natl Acad Sci U S A. 2002 Dec 10;99 Suppl 4(Suppl 4):16400-6. doi: 10.1073/pnas.182426599. Epub 2002 Aug 28. Proc Natl Acad Sci U S A. 2002. PMID: 12200548 Free PMC article.

10

Ataxin-3 is transported into the nucleus and associates with the nuclear matrix.

Tait D, Riccio M, Sittler A, Scherzinger E, Santi S, Ognibene A, Maraldi NM, Lehrach H, Wanker EE. Tait D, et al. Among authors: lehrach h. Hum Mol Genet. 1998 Jun;7(6):991-7. doi: 10.1093/hmg/7.6.991. Hum Mol Genet. 1998. PMID: 9580663

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