Van Zijl P - Search Results

1

Bis-bioreductive agents as hypoxia-selective cytotoxins: nitracrine N-oxide.

Wilson WR, Van Zijl P, Denny WA. Wilson WR, et al. Among authors: van zijl p. Int J Radiat Oncol Biol Phys. 1992;22(4):693-6. doi: 10.1016/0360-3016(92)90505-c. Int J Radiat Oncol Biol Phys. 1992. PMID: 1544839

2

Reductive chemistry of the novel hypoxia-selective cytotoxin 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.

Palmer BD, van Zijl P, Denny WA, Wilson WR. Palmer BD, et al. Among authors: van zijl p. J Med Chem. 1995 Mar 31;38(7):1229-41. doi: 10.1021/jm00007a019. J Med Chem. 1995. PMID: 7707325

3

Nitrobenzyl mustard quaternary salts: a new class of hypoxia-selective cytotoxins capable of releasing diffusible cytotoxins on bioreduction.

Denny WA, Wilson WR, Tercel M, Van Zijl P, Pullen SM. Denny WA, et al. Among authors: van zijl p. Int J Radiat Oncol Biol Phys. 1994 May 15;29(2):317-21. doi: 10.1016/0360-3016(94)90282-8. Int J Radiat Oncol Biol Phys. 1994. PMID: 8195026

4

Hypoxia-selective antitumor agents. 13. Effects of acridine substitution on the hypoxia-selective cytotoxicity and metabolic reduction of the bis-bioreductive agent nitracrine N-oxide.

Lee HH, Wilson WR, Ferry DM, van Zijl P, Pullen SM, Denny WA. Lee HH, et al. Among authors: van zijl p. J Med Chem. 1996 Jun 21;39(13):2508-17. doi: 10.1021/jm9600104. J Med Chem. 1996. PMID: 8691448

5

5-Nitro-4-(N,N-dimethylaminopropylamino)quinoline (5-nitraquine), a new DNA-affinic hypoxic cell radiosensitizer and bioreductive agent: comparison with nitracrine.

Wilson WR, Siim BG, Denny WA, van Zijl PL, Taylor ML, Chambers DM, Roberts PB. Wilson WR, et al. Among authors: van zijl pl. Radiat Res. 1992 Sep;131(3):257-65. Radiat Res. 1992. PMID: 1438685

6

Comparison of aromatic and tertiary amine N-oxides of acridine DNA intercalators as bioreductive drugs. Cytotoxicity, DNA binding, cellular uptake, and metabolism.

Siim BG, Hicks KO, Pullen SM, van Zijl PL, Denny WA, Wilson WR. Siim BG, et al. Among authors: van zijl pl. Biochem Pharmacol. 2000 Oct 1;60(7):969-78. doi: 10.1016/s0006-2952(00)00420-2. Biochem Pharmacol. 2000. PMID: 10974206

7

An experimental and mathematical model for the extravascular transport of a DNA intercalator in tumours.

Hicks KO, Ohms SJ, van Zijl PL, Denny WA, Hunter PJ, Wilson WR. Hicks KO, et al. Among authors: van zijl pl. Br J Cancer. 1997;76(7):894-903. doi: 10.1038/bjc.1997.481. Br J Cancer. 1997. PMID: 9328149 Free PMC article.

8

Sensitive liquid chromatographic assay for the basic DNA intercalator (N,N-dimethylaminoethyl)-9-amino-5-methylacridine-4-carboxamide and its nitroarylmethyl quaternary prodrugs in biological samples.

Ferry DM, van Zijl PL, Wilson WR. Ferry DM, et al. Among authors: van zijl pl. J Chromatogr B Biomed Sci Appl. 2001 Nov 5;763(1-2):149-56. doi: 10.1016/s0378-4347(01)00381-4. J Chromatogr B Biomed Sci Appl. 2001. PMID: 11710573

9

Mutagenic and clastogenic activity of nitracrine analogues in cultured V79 Chinese hamster cells.

Ferguson LR, van Zijl P. Ferguson LR, et al. Among authors: van zijl p. Mutat Res. 1988 Apr;204(4):655-63. doi: 10.1016/0165-1218(88)90069-9. Mutat Res. 1988. PMID: 3352647

10

Mutagenicity profiles of newer amsacrine analogues with activity against solid tumours: comparison of microbial and mammalian systems.

Ferguson LR, van Zijl P, Baguley BC. Ferguson LR, et al. Among authors: van zijl p. Eur J Cancer Clin Oncol. 1989 Feb;25(2):255-61. doi: 10.1016/0277-5379(89)90017-5. Eur J Cancer Clin Oncol. 1989. PMID: 2649376

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