Kwak MK - Search Results

1

Chemoprevention through the Keap1-Nrf2 signaling pathway by phase 2 enzyme inducers.

Kwak MK, Wakabayashi N, Kensler TW. Kwak MK, et al. Mutat Res. 2004 Nov 2;555(1-2):133-48. doi: 10.1016/j.mrfmmm.2004.06.041. Mutat Res. 2004. PMID: 15476857 Review.

2

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.

Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, Kensler TW. Ramos-Gomez M, et al. Among authors: kwak mk. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3410-5. doi: 10.1073/pnas.051618798. Proc Natl Acad Sci U S A. 2001. PMID: 11248092 Free PMC article.

3

Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione.

Kwak MK, Itoh K, Yamamoto M, Sutter TR, Kensler TW. Kwak MK, et al. Mol Med. 2001 Feb;7(2):135-45. Mol Med. 2001. PMID: 11471548 Free PMC article.

4

Role of phase 2 enzyme induction in chemoprotection by dithiolethiones.

Kwak MK, Egner PA, Dolan PM, Ramos-Gomez M, Groopman JD, Itoh K, Yamamoto M, Kensler TW. Kwak MK, et al. Mutat Res. 2001 Sep 1;480-481:305-15. doi: 10.1016/s0027-5107(01)00190-7. Mutat Res. 2001. PMID: 11506823 Review.

5

Antioxidative function and substrate specificity of NAD(P)H-dependent alkenal/one oxidoreductase. A new role for leukotriene B4 12-hydroxydehydrogenase/15-oxoprostaglandin 13-reductase.

Dick RA, Kwak MK, Sutter TR, Kensler TW. Dick RA, et al. Among authors: kwak mk. J Biol Chem. 2001 Nov 2;276(44):40803-10. doi: 10.1074/jbc.M105487200. Epub 2001 Aug 27. J Biol Chem. 2001. PMID: 11524419 Free article.

6

Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter.

Kwak MK, Itoh K, Yamamoto M, Kensler TW. Kwak MK, et al. Mol Cell Biol. 2002 May;22(9):2883-92. doi: 10.1128/MCB.22.9.2883-2892.2002. Mol Cell Biol. 2002. PMID: 11940647 Free PMC article.

7

Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.

Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW. Kwak MK, et al. J Biol Chem. 2003 Mar 7;278(10):8135-45. doi: 10.1074/jbc.M211898200. Epub 2002 Dec 27. J Biol Chem. 2003. PMID: 12506115 Free article.

8

Induction of phase 2 enzymes by serum oxidized polyamines through activation of Nrf2: effect of the polyamine metabolite acrolein.

Kwak MK, Kensler TW, Casero RA Jr. Kwak MK, et al. Biochem Biophys Res Commun. 2003 Jun 6;305(3):662-70. doi: 10.1016/s0006-291x(03)00834-9. Biochem Biophys Res Commun. 2003. PMID: 12763045

9

Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway.

Kwak MK, Wakabayashi N, Greenlaw JL, Yamamoto M, Kensler TW. Kwak MK, et al. Mol Cell Biol. 2003 Dec;23(23):8786-94. doi: 10.1128/MCB.23.23.8786-8794.2003. Mol Cell Biol. 2003. PMID: 14612418 Free PMC article.

10

Phase 2 enzyme induction by the major metabolite of oltipraz.

Petzer JP, Navamal M, Johnson JK, Kwak MK, Kensler TW, Fishbein JC. Petzer JP, et al. Among authors: kwak mk. Chem Res Toxicol. 2003 Nov;16(11):1463-9. doi: 10.1021/tx034154e. Chem Res Toxicol. 2003. PMID: 14615973

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