Holtz G - Search Results

1

3-[3-Fluoro-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)phenyl]-4-methylpyridine: a highly potent and orally bioavailable metabotropic glutamate subtype 5 (mGlu5) receptor antagonist.

Poon SF, Eastman BW, Chapman DF, Chung J, Cramer M, Holtz G, Cosford ND, Smith ND. Poon SF, et al. Among authors: holtz g. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5477-80. doi: 10.1016/j.bmcl.2004.09.011. Bioorg Med Chem Lett. 2004. PMID: 15482907

2

[3H]Methoxymethyl-3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine binding to metabotropic glutamate receptor subtype 5 in rodent brain: in vitro and in vivo characterization.

Anderson JJ, Rao SP, Rowe B, Giracello DR, Holtz G, Chapman DF, Tehrani L, Bradbury MJ, Cosford ND, Varney MA. Anderson JJ, et al. Among authors: holtz g. J Pharmacol Exp Ther. 2002 Dec;303(3):1044-51. doi: 10.1124/jpet.102.040618. J Pharmacol Exp Ther. 2002. PMID: 12438526

3

In vivo receptor occupancy of mGlu5 receptor antagonists using the novel radioligand [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine).

Anderson JJ, Bradbury MJ, Giracello DR, Chapman DF, Holtz G, Roppe J, King C, Cosford ND, Varney MA. Anderson JJ, et al. Among authors: holtz g. Eur J Pharmacol. 2003 Jul 18;473(1):35-40. doi: 10.1016/s0014-2999(03)01935-6. Eur J Pharmacol. 2003. PMID: 12877935

4

Metabotropic glutamate receptor 5 antagonist-induced stimulation of hypothalamic-pituitary-adrenal axis activity: interaction with serotonergic systems.

Bradbury MJ, Giracello DR, Chapman DF, Holtz G, Schaffhauser H, Rao SP, Varney MA, Anderson JJ. Bradbury MJ, et al. Among authors: holtz g. Neuropharmacology. 2003 Apr;44(5):562-72. doi: 10.1016/s0028-3908(03)00048-0. Neuropharmacology. 2003. PMID: 12668042

5

Reduced cerebrospinal fluid levels of alpha-secretase-cleaved amyloid precursor protein in aged rats: correlation with spatial memory deficits.

Anderson JJ, Holtz G, Baskin PP, Wang R, Mazzarelli L, Wagner SL, Menzaghi F. Anderson JJ, et al. Among authors: holtz g. Neuroscience. 1999;93(4):1409-20. doi: 10.1016/s0306-4522(99)00244-4. Neuroscience. 1999. PMID: 10501466

6

Reductions in beta-amyloid concentrations in vivo by the gamma-secretase inhibitors BMS-289948 and BMS-299897.

Anderson JJ, Holtz G, Baskin PP, Turner M, Rowe B, Wang B, Kounnas MZ, Lamb BT, Barten D, Felsenstein K, McDonald I, Srinivasan K, Munoz B, Wagner SL. Anderson JJ, et al. Among authors: holtz g. Biochem Pharmacol. 2005 Feb 15;69(4):689-98. doi: 10.1016/j.bcp.2004.11.015. Epub 2005 Jan 7. Biochem Pharmacol. 2005. PMID: 15670587

7

Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice.

Lamb BT, Bardel KA, Kulnane LS, Anderson JJ, Holtz G, Wagner SL, Sisodia SS, Hoeger EJ. Lamb BT, et al. Among authors: holtz g. Nat Neurosci. 1999 Aug;2(8):695-7. doi: 10.1038/11154. Nat Neurosci. 1999. PMID: 10412057 No abstract available.

8

Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice.

Lesuisse C, Xu G, Anderson J, Wong M, Jankowsky J, Holtz G, Gonzalez V, Wong PC, Price DL, Tang F, Wagner S, Borchelt DR. Lesuisse C, et al. Among authors: holtz g. Hum Mol Genet. 2001 Oct 15;10(22):2525-37. doi: 10.1093/hmg/10.22.2525. Hum Mol Genet. 2001. PMID: 11709540

9

Altered metabolism of familial Alzheimer's disease-linked amyloid precursor protein variants in yeast artificial chromosome transgenic mice.

Lamb BT, Call LM, Slunt HH, Bardel KA, Lawler AM, Eckman CB, Younkin SG, Holtz G, Wagner SL, Price DL, Sisodia SS, Gearhart JD. Lamb BT, et al. Among authors: holtz g. Hum Mol Genet. 1997 Sep;6(9):1535-41. doi: 10.1093/hmg/6.9.1535. Hum Mol Genet. 1997. PMID: 9285791

10

Accuracy in diagnosing deep and pelvic vein thrombosis in primary care: an analysis of 395 cases seen by 58 primary care physicians.

El Tabei L, Holtz G, Schürer-Maly C, Abholz HH. El Tabei L, et al. Among authors: holtz g. Dtsch Arztebl Int. 2012 Nov;109(45):761-6. doi: 10.3238/arztebl.2012.0761. Epub 2012 Nov 9. Dtsch Arztebl Int. 2012. PMID: 23227128 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

86 results

Search Page

Filters