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Increased sensitivity to endothelial nitric oxide (NO) contributes to arterial normotension in mice with vascular smooth muscle-selective deletion of the atrial natriuretic peptide (ANP) receptor.
Sabrane K, Gambaryan S, Brandes RP, Holtwick R, Voss M, Kuhn M. Sabrane K, et al. Among authors: kuhn m. J Biol Chem. 2003 May 16;278(20):17963-8. doi: 10.1074/jbc.M213113200. Epub 2003 Mar 11. J Biol Chem. 2003. PMID: 12637561 Free article.
We recently generated mice with selective deletion of the ANP receptor, guanylyl cyclase-A (GC-A), in vascular smooth muscle (SMC GC-A knockout (KO) mice) and reported that resting arterial blood pressure was completely normal in spite of clear abolition of the direct vasodilatin …
We recently generated mice with selective deletion of the ANP receptor, guanylyl cyclase-A (GC-A), in vascular smooth muscle (SMC GC-A knock …
1,384 results