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Phase I and pharmacokinetic study of XR11576, an oral topoisomerase I and II inhibitor, administered on days 1-5 of a 3-weekly cycle in patients with advanced solid tumours.
de Jonge MJ, Kaye S, Verweij J, Brock C, Reade S, Scurr M, van Doorn L, Verheij C, Loos W, Brindley C, Mistry P, Cooper M, Judson I. de Jonge MJ, et al. Among authors: scurr m. Br J Cancer. 2004 Oct 18;91(8):1459-65. doi: 10.1038/sj.bjc.6602178. Br J Cancer. 2004. PMID: 15452551 Free PMC article. Clinical Trial.
A Phase I study of the angiogenesis inhibitor SU5416 (semaxanib) in solid tumours, incorporating dynamic contrast MR pharmacodynamic end points.
O'Donnell A, Padhani A, Hayes C, Kakkar AJ, Leach M, Trigo JM, Scurr M, Raynaud F, Phillips S, Aherne W, Hardcastle A, Workman P, Hannah A, Judson I. O'Donnell A, et al. Among authors: scurr m. Br J Cancer. 2005 Oct 17;93(8):876-83. doi: 10.1038/sj.bjc.6602797. Br J Cancer. 2005. PMID: 16222321 Free PMC article. Clinical Trial.
Sarcoma.
Scurr M, Judson I. Scurr M, et al. Cancer Chemother Biol Response Modif. 2003;21:637-53. doi: 10.1016/s0921-4410(03)21030-9. Cancer Chemother Biol Response Modif. 2003. PMID: 15338767 Review. No abstract available.
Soft-tissue and bone sarcomas.
Scurr M, Judson I. Scurr M, et al. Cancer Chemother Biol Response Modif. 2005;22:591-604. doi: 10.1016/s0921-4410(04)22026-9. Cancer Chemother Biol Response Modif. 2005. PMID: 16110630 Review. No abstract available.
70 results